Nature Communications
Articles in this Issue
Myoferlin is a component of late-stage vRNP trafficking vesicles for enveloped RNA viruses
Abstract The Rab11 endosomal recycling pathway is exploited by important respiratory RNA viruses such as IAV and RSV, aiding viral egress from the apical surface of polarized epithel...
Discovery of antimicrobial peptides targeting Acinetobacter baumannii via a pre-trained and fine-tuned few-shot learning-based pipeline
Cryo-EM structures of bacteriophage T4 portal-neck assembly intermediates reveal a viral genome retention mechanism
Antiparallel stacking of Csu pili drives Acinetobacter baumannii 3D biofilm assembly
Abstract Many Gram-negative nosocomial pathogens rely on adhesive filaments, known as archaic chaperone-usher pili, to establish stress- and drug-resistant, mult...
Heterogeneous multicopy of blaCTX-M variants on the same plasmid enhances evolutionary adaptability in clinical Klebsiella pneumoniae
Abstract Pathogenic bacteria continually evolve under antimicrobial pressure through acquired resistance genes, making it crucial to understand their evolutionar...
Analysis of the transcriptomic and metabolomic landscape of prostate cancer with different anatomical origins using snFLARE-seq and mxFRIZNGRND
Abstract Prostate cancer cells of different anatomical locations display remarkable heterogeneity. This poses a challenge to the clinical relevance of pre-clinical models and the eff...
Hepatocytes functionally reprogrammed by KIAA1199-high colorectal cancer cells favour the accumulation of pro-metastatic Egr1+ neutrophils
Abstract Colorectal cancer liver metastasis (CRLM) is a leading cause of mortality, driven by poorly defined molecular interactions within the hepatic niche. Her...
Neuromorphic photonic computing with an electro-optic analog memory
Abstract In neuromorphic photonic systems, device operations are typically governed by analog signals, necessitating digital-to-analog converters (DAC) and analog-to-digital converte...
Radical footprinting in mammalian whole blood
Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial
A combinatorial synthetic strategy for developing genome-editing protein-delivery agents targeting mouse retina
Abstract CRISPR/Cas9-based gene-editing technologies offer promise for treating inherited retinal diseases (IRDs), however safe and efficient ocular delivery of precision editors rem...
The photolyase/cryptochrome of Aspergillus nidulans senses oxidative stress and shuttles from nuclei to mitochondria
Abstract Cryptochromes are photoreceptors with functions in the entrainment of circadian clocks or as proposed magnetoreceptors in birds or as light-independent...
A 3D gut-brain-vascular platform for bidirectional crosstalk in gut-neuropathogenesis
Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer
In-memory multilevel control of generic SO(m) holonomy in photonics
Physiological basis of resolution acuity in vision
Identification of protein precursor for thyroid hormone synthesis in basal chordate ascidian Styela clava
Theory-independent monitoring of the decoherence of a superconducting qubit with generalized contextuality
Abstract Characterizing the nonclassicality of quantum systems under minimal assumptions is an important challenge for quantum foundations and technology. Here we introduce a theory-...
Ultralong octupole moment switching driven by twin topological spin structures
Direct observation and quantification of single nanocondensates of the low complexity domain of TDP-43
Assessing conformation validity and rationality of deep learning-generated 3D molecules
Local PI(4,5)P2 synthesis by septin-associated PIPKIγ isoforms controls centralspindlin association with the midbody during cytokinesis
Abstract Cytokinesis critically depends on phosphatidylinositol 4,5-bisphosphate [PI(4,5)P 2 ]. Synthesis of PI(4,5)P...
Synthesis of 2D amorphous carbons via energy-autonomous carbonization of polyaniline upon decomposition of HClO₄
Abstract Despite centuries of advancement, the synthesis of carbon materials remains heavily reliant on energy-intensive thermal processes. Conventional methods...
Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation
Abstract How adhesion G protein-coupled receptors (aGPCRs) control development remains unclear. aGPCR Adgrg6/Gpr126 has been associated with heart trabeculation....