Nature Communications
Articles in this Issue
An integrative structural biology approach reveals the dynamic organization of the R2SP quaternary chaperone complex
Sequencing DNA methylation and hydroxymethylation at co-occurring chromatin features
Abstract Epigenetic modifications govern chromatin dynamics and cell state. However, current methods cannot simultaneously resolve the presence of multiple DNA modifications at co-oc...
Molecular determinant of low-voltage dependence of human Nav1.7 inactivation revealed by efficacy-based Nav1.7 selective inhibitor
Evidence of megathrust earthquakes and seismic supercycles in subtropical Japan from millennia-old coral microatolls
Abstract Megathrust earthquakes in subduction zones often go unreported because they are rare and the historical record is short. On the Ryukyu subduction zone of southwestern Japan,...
An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models
Abstract The mosquito-transmitted Zika virus (ZIKV) poses a global health threat, with no approved antiviral drugs or vaccines currently available. Here, we repo...
Photosynergetic ligand-exchange for modular synthesis of copper nanoclusters
Global application of radiative cooling in grain storage
Chemoenzymatic synthesis of pentalenolactones via stereoselective Riley oxidation by engineered P450BM3
Experimental quantification of hydrogen content in the Earth’s core
Abstract Earth’s core has long been speculated to be the largest reservoir of hydrogen (H) on the planet. However, current estimates of its H content involve substantial uncertaintie...
Virus glycoprotein nanodisc platform for vaccine analytics
Abstract Transmembrane glycoproteins of enveloped viruses are targets of neutralizing antibodies and essential vaccine antigens. mRNA-LNP technology allows in vivo expression of tran...
Preoptic kisspeptin-nNOS-GnRH (KiNG) neuronal network regulates LH rhythmicity through activation-inhibition in mice
Ultrafast scintillating metal-organic framework films
Over a century of global decline in the growth performance of marine fishes
Abstract Human-driven pressures are causing large-scale changes in the ecologies and life histories of fishes. Growth performance is a composite life-history tra...
Ultrafast visual perception beyond human capabilities enabled by motion analysis using synaptic transistors
Author Correction: Whole-body CD8+ T-cell PET imaging in patients with large B-cell lymphoma before and during CD19-directed CAR T-cell therapy: a phase 2 study
Degraders of the dengue virus capsid protein exhibit differentiated pharmacology relative to capsid inhibitors
Abstract Due to the limited size of viral genomes, most viral proteins are multifunctional; yet most direct-acting antivirals are designed as single-function inh...
Persistent representation of a prior schema in the orbitofrontal cortex facilitates learning of a conflicting schema
Abstract Schemas allow efficient behavior in new situations, but reliance on them can impair flexibility when new demands conflict. Evidence implicates the orbitofrontal cortex (OFC)...
Triggering action potentials of a single neuron by multiphoton excitation elicits visually guided behavior
Hypersensitive detection of single millimeter vascular emboli from adhesive in vivo
Abstract Surgical adhesives are widely used in clinical practice but pose a significant risk of severe vascular embolism complications. Nevertheless, there are currently no non-invas...