Nature Communications
Articles in this Issue
Trifunctional flavoenzyme-catalyzed asymmetric 4-alkyl-butenolide assembly in avenolide biosynthesis
Pan-RAF inhibitor exarafenib targets BRAF class II/III NSCLC and reveals ARAF-KSR1 resistance and combination strategies
Abstract Oncogenic BRAF mutations, including those in non-small cell lung cancer (NSCLC), are classified as Class I, II, or III. While approved therapies exist for BRAF Class I mutan...
FANCD2 restrains fork progression and prevents fragility at early origins upon re-replication
Cross ionization mode chemical similarity prediction between tandem mass spectra in metabolomics
Abstract Mass spectrometry is a cornerstone of untargeted metabolomics, enabling the characterization of metabolites in both positive and negative ionization modes. However, comparis...
Convergent extreme reductive evolution in ancient planthopper symbioses
Abstract Strictly heritable endosymbiotic bacteria that provide limiting nutrients to sap-sucking hemipteran insects are known for their highly reduced genomes c...
Engineering a cytochrome P450 enzyme as a peroxygenase for selective hydroxylation of steroids
Cooperative anion activation at a cobalt center through ion pairing and ligand design
In situ-formed C-N anchors embedded into Sn-based negative electrodes for long-life Na-ion batteries
Whole-genome sequencing analysis of anthropometric traits in 672,976 individuals reveals convergence between rare and common genetic associations
Abstract GWAS have generally focused on common variants from genotyping arrays or rare protein-coding variants from exome sequencing. Here, we use whole-genome s...
Coherence transfer from optically induced THz magnons to charges
Abstract The digital economy, society and politics are increasingly shaped by cloud-based data. The advancement of transformative technologies, such as artificial intelligence, is pl...
Realistic atomic model for charge storage and charging dynamics of amorphous porous carbons
Shifting winter atmospheric teleconnections to the North Pacific reconcile Younger-Dryas and Holocene δ18O signals
Abstract Using Alaskan lake sediment oxygen isotope records (δ 18 O), which trace the δ 18...
Predicting instabilities in transient landforms and interconnected ecosystems
Abstract Many parts of the Earth system are thought to have multiple stable equilibrium states, with the potential for catastrophic shifts between them. Common methods to assess syst...
The contribution of sea-ice recrystallization to the Arctic snowpack
Genomics of rafting crustaceans reveals adaptation to climate change in tropical oceans
Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma
Abstract GATA6 promotes epithelial phenotypes and limits epithelial-to-mesenchymal (EMT) transition in pancreatic ductal adenocarcinoma (PDAC). Here we show that...
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection
Abstract Influenza virus infections can cause severe complications such as Acute Necrotizing Encephalopathy (ANE), which is characterised by a rapid onset of pathological inflammatio...
Scalable modular design of solid oxide fuel cell systems for enhanced large-scale power generation
Abstract The increasing demand for renewable energy integration and scalable power generation highlights the need for efficient and cost-effective solid oxide fuel cell systems. In t...
Highly tunable band structure in ferroelectric R-stacked bilayer WSe2
Abstract Transition metal dichalcogenide homobilayers unite two frontiers of quantum materials research: sliding ferroelectricity, arising from rhombohedral stac...
Author Correction: DKN-01 and tislelizumab as second-line therapy in DKK1-high gastroesophageal adenocarcinoma: DisTinGuish trial part B
Mycobacterium tuberculosis modulates phosphorylation of host ATP6V1E1 to promote intracellular survival
Abstract Intracellular pathogens such as Mycobacterium tuberculosis (Mtb) can promote their survival within infected cell...
Enhancing film bulk acoustic resonators performance by optimizing AlN seed layer crystallinity and polarity alignment
Subjective nature of path information in quantum mechanics
Abstract Common sense suggests that a particle must have a definite origin if its full path information is available. In quantum mechanics, the knowledge of path information is captu...