Nature Communications

Shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters

Thijs W. Ettema, Satomi Inaba-Inoue, Chancievan Thangaratnarajah et al. Apr 15, 2026 10.1038/s41467-026-71633-3

Abstract SbmA is a membrane transporter from Escherichia coli that imports antimicrobial peptides. SbmA belongs to the Sb...

The genetic basis for DNA methylation variation across tissues and development

Jonathan Rosenski, Ofra Sabag, Eitan Marcus et al. Apr 15, 2026 10.1038/s41467-026-71693-5

GID/CTLH E3 ligase complex control cell fate programs for sexual development of Plasmodium falciparum

Danushka S. Marapana, Sash Lopaticki, Balu Balan et al. Apr 15, 2026 10.1038/s41467-026-69183-9

Persistent organic pollutant concentrations in human pancreas correlate with markers of beta cell dysfunction

Myriam P. Hoyeck, Ma. Enrica Angela Ching, Jana Palaniyandi et al. Apr 15, 2026 10.1038/s41467-026-71847-5

Peritectic engineering enhanced thermoelectrics for smart thermal messaging devices

Jiwu Xin, Ziwang Luo, Wang Li et al. Apr 15, 2026 10.1038/s41467-026-71799-w

A multimodal approach for visualizing and identifying electrophysiological cell types in vivo

Eric Kenji Lee, Asım E. Gül, Greggory Heller et al. Apr 15, 2026 10.1038/s41467-026-71331-0

Assembling a single active pocket from enzyme and metal modules for simultaneously catalyzing oxidation-reduction cascades

Yunkai Fan, Jia Hu, Qilu Wu et al. Apr 15, 2026 10.1038/s41467-026-72061-z

Dipolar interaction-mediated molecular anchoring electrolyte enables wide-temperature sodium-ion batteries with enhanced safety and durability

Yong-Li Heng, Zhen-Yi Gu, Yuan-Zheng Tang et al. Apr 15, 2026 10.1038/s41467-026-71861-7

Meta-encoder: a unified integration framework for multiple pathological foundation models in cancer detection

Ruitian Gao, Zhaochang Yang, Xin Yuan et al. Apr 15, 2026 10.1038/s41467-026-71558-x

Supramolecular engineering of amyloid-inspired tripeptide assemblies enabling tunable piezoelectricity

Yehong Huo, Shuaijie Liu, Bingbing Yang et al. Apr 15, 2026 10.1038/s41467-026-71734-z

Author Correction: Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution

Nathalie Khoury, Michelle E. Pizzo, Claire B. Discenza et al. Apr 15, 2026 10.1038/s41467-026-71806-0

Temporal-Spatial Fusion Vision Hardware Enables Streamlined In-Sensor Computing for Dynamic Scenes

Yi Wu, Wenjie Deng, Ruihao Liu et al. Apr 15, 2026 10.1038/s41467-026-71907-w

Spin magnetic proximity effect in graphene superlattices

Yijie Lin, Daniel Burrow, Jesus C. Toscano-Figueroa et al. Apr 15, 2026 10.1038/s41467-026-71915-w

Structural basis for protein-free catalysis by ribonuclease P ribozyme

Yun-Tzai Lee, Maximilia F. S. Degenhardt, Ilias Skeparnias et al. Apr 15, 2026 10.1038/s41467-026-71597-4

Abstract Ribonuclease P (RNase P) is an essential metallonuclease found in all three domains of life. However, the structural basis for the ancient RNase P RNA c...

Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence

Tianxiang Zheng, Li Tao, Qiuhua Gao et al. Apr 15, 2026 10.1038/s41467-026-71532-7

Abstract Mixed urinary incontinence, involving concurrent or diagnostically unclear components of urge- and stress-related dysfunction, remains poorly addressed by current therapeuti...

SLC1A5 prevents aortic aneurysm and dissection by glutaminolytic-epigenetic orchestration of vascular smooth muscle cell homeostasis

Pinglian Yang, Zhechang Gao, Weile Ye et al. Apr 15, 2026 10.1038/s41467-026-71856-4

All-in-One photo-biocatalysis system for sustainable chemical transformations

Si Liu, Siyao Zhang, Yan Sun Apr 15, 2026 10.1038/s41467-026-72050-2

Cardiac reprogramming via transient overexpression of P-glycoprotein alleviates doxorubicin-induced cardiotoxicity in mice and pigs

Yixin Zhang, Weirun Li, Yingxian Xiao et al. Apr 15, 2026 10.1038/s41467-026-71843-9

Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer

Verena Wagner, Laura Bousset, Mariana Ascensão-Ferreira et al. Apr 15, 2026 10.1038/s41467-026-71564-z

Abstract RAS family proteins, including HRAS, NRAS, and KRAS, are frequently mutated in cancer. Although there has been recent success in designing inhibitors that target oncogenic R...

A deep learning–based digital biopsy for predicting early recurrence in gastric cancer

Ping’an Ding, Sheng Chen, Honghai Guo et al. Apr 15, 2026 10.1038/s41467-026-71347-6

Single-nucleus brain transcriptomics reveals microglia dysfunction in multiple system atrophy

Rasmus Rydbirk, Frederik Nørby Friis Sørensen, Jonas Folke et al. Apr 15, 2026 10.1038/s41467-026-71525-6

Fractional crystallization of colloids by sequential tuning of depletion forces

Sehee Yang, Sanghyuk Park, Yongseok Jung et al. Apr 15, 2026 10.1038/s41467-026-72000-y

Demethylation-primed tandem CD19/CD20 CAR T cells in relapsed/refractory B-cell lymphoma: a phase I/II trial

Chunmeng Wang, Yelei Guo, Fuxin Han et al. Apr 15, 2026 10.1038/s41467-026-72040-4

Author Correction: A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities

Zhenyu Yang, Shiyou Wei, Hao Duan et al. Apr 15, 2026 10.1038/s41467-026-71972-1

Thyrotropin-releasing hormone neurons of different hypothalamic nuclei increase energy expenditure

Andreea Constantinescu, Akila Chandrasekar, Lena Kleindienst et al. Apr 15, 2026 10.1038/s41467-026-71617-3

Abstract Several neuronal populations in the hypothalamus and brainstem express thyrotropin-releasing hormone (TRH). While TRH neurons in the paraventricular nucleus (PVN) regulate t...

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