Nature Communications
Articles in this Issue
SpatialCOC: an integrative framework for spatial continuous mapping and cross-omics correction in spatial multi-omics data
Abstract Integrating spatial multi-omics data presents significant challenges, particularly in uncovering the spatial patterns of cells and deciphering the real regulatory mechanisms...
Atomistic characterization of the maturation mechanisms in the HIV-1 capsid domain
Abstract During HIV-1 maturation, capsid proteins (CA) are proteolytically cleaved from the immature Gag lattice and undergo conformational transitions in which the amino-terminal an...
Clonal biases dictate availability of colonic cancer driver mutations for transformation
Abstract Aged normal tissues harbour cancer mutations predisposing to transformation. However, how different pro-oncogenic events in the human colon compare in f...
Unlocking the ionic transport dynamics modulated by concentration artifacts of Li(Na)-ion batteries via operando optical fiber spectroscopy
Immune-induced TCR-like antibodies regulate specific T cell response in mice
Abstract Antigen-specific regulation of T cell response is crucial for limiting hyperimmune response. However, the molecular mechanisms governing specific immune regulation remain un...
2040 greenhouse gas reduction targets and energy transitions in line with the EU Green Deal
Abstract The European Green Deal aims to guide the European Union towards achieving net-zero greenhouse gas emissions by implementing a comprehensive set of policy initiatives and le...
Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation
Precision cardiovascular risk prediction in type 1 diabetes: An IMI2 SOPHIA analysis
Abstract Cardiovascular disease (CVD) is a major long-term complication and the leading cause of morbidity and mortality among individuals with type 1 diabetes (T1D), with a substant...
Rhenium isotopes reveal enhanced rock organic carbon oxidation over the Toarcian Oceanic Anoxic Event
Abstract Weathering plays a central role in the geological carbon cycle. Silicate mineral weathering is invoked as a stabilizing feedback on CO...
Friction-differentiated separation of alkali ions through two-dimensional nanochannels based on niobate perovskite
Dew formation is associated with higher ecosystem productivity across diverse ecosystems
Higher-order neuromorphic Ising machines—autoencoders and Fowler-Nordheim annealers are all you need for scalability
Piezocatalytic reforming of plastics into high-value chemicals
Structurally exclusive Teneurin complexes orchestrate divergent programs in early cortical development
Abstract Cortical migration is a complex process in which neurons migrate along radial glial cells (RGC) to form functional layers. Teneurins (Ten1-4) play a role by interacting with...
Structure of a contractile injection system in Salmonella enterica subsp. salamae
Evolution of the reptile spine reveals independent trajectories to axial skeletal complexity in amniotes
Abstract The evolution of complex, highly regionalized and heterogeneous axial skeletons within amniotes has traditionally been considered a unique characteristic of Pan-Mammalia, wi...
Unusual terminational effect on atomic ripple of Ti3C2Tx MXenes
The genomic basis of adaptive leaf variation in the Galápagos giant daisies
Abstract Scalesia (Asteraceae) is the largest endemic plant genus of the Galápagos archipelago and an example of adaptive radiation. While...
Chirality-selective optical transport of nanoparticles in the evanescent field of a nanofibre
Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization
Abstract Gephyrin, the principal scaffolding protein of inhibitory postsynaptic densities, clusters glycine and GABA A re...
Activation mechanism of the full-length histidine kinase LvrB from pathogenic Leptospira
Abstract Pathogenic Leptospira modulate their virulence via the Lvr signaling system, with the histidine kinase LvrB bein...
Folded domains impose structural heterogeneity and attenuated dynamics in biomolecular condensates
Regional drying over the Western U.S. driven by enhanced atmospheric subsidence amid global moistening from 1980 to 2020
Abstract As the global climate has warmed anthropogenically over the past decades, the atmosphere across most of the globe has experienced significant moistening, except for a “moist...
Beyond metabolic dormancy: metabolic rewiring in bacterial persistence
Electrically reconfigurable extended lasing state in an organic liquid-crystal microcavity
Abstract Small-footprint, low-power, and reprogrammable arrays of coupled coherent emitters are highly sought in modern nanophotonics. Among existing solutions, only inorganic semico...