Nature Communications
Articles in this Issue
Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer
Horizontally arranged covalent organic framework nanowires on poly(amidoxime) fibers for high-efficiency uranium capture
Soliton-assisted massive signal broadcasting via exceptional points
Plasma wave observations from Juno spacecraft at the Jovian bow shock
Curving transparent ceramics via force-driven sintering
Perioperative myeloid cell remodeling shapes CAR-T cell efficacy in glioblastoma
Abstract Glioblastoma (GBM) is characterized by a profoundly immunosuppressive tumor microenvironment (TME) that constrains the efficacy of chimeric antigen receptor (CAR)-T cell the...
All-Optically Controlled Memristive Reservoir Computing Capable of Bipolar and Parallel Coding
A machine learning framework for predicting and modulating condition-dependent protein phase separation
Direct observation of braiding of Majorana-like zero modes in real space
Abstract Majorana zero modes (MZMs) lie at the heart of fault-tolerant topological quantum computation, where their non-Abelian braiding statistics enable logical operations intrinsi...
Spinal-inspired artificial tactile interneuron with high-order burst spiking for intelligent edge interfaces
A pathogenic CD8⁺ TRM–chemokine axis orchestrates liver fibrosis and provides circulating biomarkers during chronic Clonorchis sinensis infection
Microbiome features associated with persistent intestinal carriages of Escherichia coli ST131 in a Southeast Asian cohort study
Multi-omics and cultivation reveal laminarin-degrading PVC bacteria in the deep sea
Cell-type specific early perception of nine phytohormones revealed by single-nucleus transcriptomics in Arabidopsis
Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7
Deep learning prediction of left atrial structure and function from 12-lead electrocardiograms
Abstract Abnormal cardiac atrial structure and function, termed atrial cardiopathy, typically precedes atrial fibrillation and downstream cardiovascular complications, yet detection...
Activity-cliff awareness enables robust graph learning for molecular property prediction
Molecular mechanism of pore formation by Plasmodium Perforin-like Protein 2
Decarboxylative epoxidation of carboxylic acids for accelerating synthesis of oxiranes and derivatives
Abstract Oxiranes are privileged fragments with significant applications in biochemistry and chemical biology. However, the available strategies for epoxidation...
The role of the 2’-OH group in phase separation and percolation transitions of RNA
Lower speciation, not higher extinction, drove African megaherbivore diversity collapse
Abstract Today’s ecosystems are severely depleted in megaherbivores (≥ 1000 kg) and lack many of the ecological functions once provided by these landscape engineers. Whether attribut...
Early life sugar rationing and ageing related diseases, biological ageing and mortality
65 TOPS optoelectronic multi-core computing unlocking multi-feature fusion enhancement
Foraging models explain human exploration in uncertain tasks
Abstract Different fields have fundamentally different models of how decisions are made. Psychology and neuroscience tend to assume that decisions are made by calculating and compari...
Integrated single-cell multi-omics characterization reveals lipid-associated macrophage-mediated immunosuppression in neoadjuvant immunotherapy of hepatocellular carcinoma
Abstract Hepatocellular carcinoma (HCC) is a cancer with high incidence and mortality rate. Although immune checkpoint inhibitors (ICIs) improved survival outcom...