A pathogenic CD8⁺ TRM–chemokine axis orchestrates liver fibrosis and provides circulating biomarkers during chronic Clonorchis sinensis infection

Xinyue Du; Jiashun Li; Xin Wang; Wenyu Wu; Tingjun Zhu; Huibo Yan; Chenyun Wu; Yuanyuan Li; Yuwei Gao; Haibo Yi; Kokouvi Kassegne; Xiangwei Li; Xiaoyin Niu; Helena Helmby; Samuel C. Wassmer; Youqiong Ye; Banchob Sripa; Guangjie Chen; Menbao Qian; Zhaojun Wang

doi:10.1038/s41467-026-76175-2

A pathogenic CD8⁺ TRM–chemokine axis orchestrates liver fibrosis and provides circulating biomarkers during chronic Clonorchis sinensis infection

X Xinyue Du J Jiashun Li X Xin Wang W Wenyu Wu T Tingjun Zhu H Huibo Yan C Chenyun Wu Y Yuanyuan Li (State Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China) Y Yuwei Gao H Haibo Yi K Kokouvi Kassegne X Xiangwei Li X Xiaoyin Niu H Helena Helmby S Samuel C. Wassmer Y Youqiong Ye B Banchob Sripa (Department of Tropical Medicine, Faculty of Medicine, Tropical Disease Research Center, Khon Kaen University) G Guangjie Chen M Menbao Qian Z Zhaojun Wang

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Article Details

Journal Nature Communications

Volume / Issue Vol. 1, Issue 1

Published July 31, 2026

DOI 10.1038/s41467-026-76175-2

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (20)

X

Xinyue Du

J

Jiashun Li

X

Xin Wang

W

Wenyu Wu

T

Tingjun Zhu

H

Huibo Yan

C

Chenyun Wu

Y

Yuanyuan Li

State Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China

Y

Yuwei Gao

H

Haibo Yi

K

Kokouvi Kassegne

X

Xiangwei Li

X

Xiaoyin Niu

H

Helena Helmby

S

Samuel C. Wassmer

Y

Youqiong Ye

B

Banchob Sripa

Department of Tropical Medicine, Faculty of Medicine, Tropical Disease Research Center, Khon Kaen University

G

Guangjie Chen

M

Menbao Qian

Z

Zhaojun Wang

A pathogenic CD8⁺ TRM–chemokine axis orchestrates liver fibrosis and provides circulating biomarkers during chronic Clonorchis sinensis infection

Article Details

Journal Info

Authors (20)

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