Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7

Camilla Maffezzini; Raffaele Iennaco; Andrea Scolz; Simone Maestri; Christian Landles; Georgina F. Osborne; Marta M. Bronzini; Camilla Trovesi; Thomas Carzaniga; Luca Casiraghi; Jimena Quiros Ramirez; Thomas F. Vogt; Dan P. Felsenfeld; Tommaso Bellini; Chiara Zuccato; Gillian P. Bates; Elena Cattaneo

doi:10.1038/s41467-026-76208-w

Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7

C Camilla Maffezzini R Raffaele Iennaco A Andrea Scolz S Simone Maestri C Christian Landles G Georgina F. Osborne M Marta M. Bronzini C Camilla Trovesi T Thomas Carzaniga L Luca Casiraghi J Jimena Quiros Ramirez T Thomas F. Vogt D Dan P. Felsenfeld T Tommaso Bellini (Dipartimento di Biotecnologie Mediche e Medicina Traslazionale) C Chiara Zuccato G Gillian P. Bates E Elena Cattaneo

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Article Details

Journal Nature Communications

Volume / Issue Vol. 1, Issue 1

Published July 31, 2026

DOI 10.1038/s41467-026-76208-w

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

C

Camilla Maffezzini

R

Raffaele Iennaco

A

Andrea Scolz

S

Simone Maestri

C

Christian Landles

G

Georgina F. Osborne

M

Marta M. Bronzini

C

Camilla Trovesi

T

Thomas Carzaniga

L

Luca Casiraghi

J

Jimena Quiros Ramirez

T

Thomas F. Vogt

D

Dan P. Felsenfeld

T

Tommaso Bellini

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

C

Chiara Zuccato

G

Gillian P. Bates

E

Elena Cattaneo

Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7

Article Details

Journal Info

Authors (17)

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