Journal of Clinical Oncology
Articles in this Issue
Basic palliative care assessments in the treatment of urological oncology patients: A prospective cross-sectional study.
e24069 Background: Current guidelines on palliative care in oncological patients recommend assessing physical, psychologic...
Proton beam therapy versus interventional procedures for hepatocellular carcinoma: A systematic review and meta-analysis of comparative studies.
e16280 Background: Proton beam therapy (PBT) is increasingly used for hepatocellular carcinoma (HCC) due to its dosimetric...
Forecasting the durability of overall survival benefit with gemtuzumab ozogamicin in acute myeloid leukemia: A cumulative and time-series meta-analysis.
e18525 Background: Gemtuzumab ozogamicin (GO) has demonstrated survival benefits in patients with acute myeloid leukemia (...
Non-operative management in mismatch repair deficient (dMMR) esophagogastric cancer (EGC) following immune checkpoint inhibition (ICI).
4078 Background: ICI achieves deep and durable responses in patients with dMMR and microsatellite instability-high (MSI-H)...
Evaluation of the combination of regorafenib + avelumab in patients with HPV-associated cancer: The phase II REGOMUNE study.
2517 Background: HPV-associated malignancies—including cervical, anal, head and neck, and penile cancers—form a biological...
Incidental breast findings identified on non-breast imaging: A multi-facility real-world analysis and implications for early detection.
e12565 Background: Breast cancer screening relies primarily on age- and risk-based criteria and dedicated breast imaging....
Molecular subtype and survival in inflammatory breast cancer: A contemporary population-based analysis.
e13088 Background: Inflammatory breast cancer (IBC) is a rare and highly aggressive form of breast cancer with persistentl...
Real-world outcomes of bispecific antibodies in relapsed/refractory (R/R) follicular lymphoma (FL).
7010 Background: Mosunetuzumab (mosun) and epcoritamab (epco) are bispecific antibodies (BsAbs) approved for R/R FL, with...
Racial/ethnic and age-related disparities in contralateral breast cancer risk among survivors: SEER MP-SIR analysis (2000–2022).
e12698 Background: Contralateral breast cancer (CBC) is a persistent survivorship risk, with prior SEER data showing eleva...
Cell-free DNA fragmentomics as an enabler of tumor-of-origin classification using a commercial targeted cfDNA panel.
3059 Background: Analysis of cell-free DNA (cfDNA) fragmentation patterns (“fragmentomics”) has emerged as a powerful appr...
Large-scale EMR-based machine learning for early risk stratification of lung cancer.
e20015 Background: Lung cancer is the leading cause of cancer-related mortality worldwide. Early detection is crucial for...
Optimizing the ER cutoff: Using ER≥50% to define a distinct HER2+ subgroup characterized by low pCR rates, ADC resistance, and CDK4 dependency.
e12646 Background: While estrogen receptor (ER)-positive/HER2-positive breast cancer generally demonstrates better long-te...
Chemo-immunotherapy (Chemo-ICI) versus chemotherapy (Chemo) alone as a first-line therapy (1L) in extensive-stage small cell lung cancer (ES-SCLC): An individual patient data (IPD)–based synthetic meta-analysis from randomized control trials (RCTs).
e20164 Background: SCLC is an aggressive high-grade neuroendocrine cancer with a high propensity for early metastasis, oft...
Clinical outcomes of patients with TP53 pathway alterations by treatment type: The MD Anderson Cancer Center IMPACT 2 study.
3152 Background: TP53 pathway alterations are found in over 50% of human cancers, with variable frequency across tumor typ...
Safety and efficacy results of the phase 2 study of silevertinib (BDTX-1535) in treatment-naïve patients with non-small cell lung cancer with non-classical EGFR mutations.
8519 Background: Non-classical mutations (NCM) of epidermal growth factor receptor (EGFR) represent a broad group of oncog...
A phase II, single-arm study of romiplostim N01 for cancer treatment–induced thrombocytopenia in leukemia patients.
6550 Background: Cancer Treatment-Induced Thrombocytopenia (CTIT) poses a significant challenge in leukemia treatment, inc...
Outpatient rehabilitation for adults with soft tissue sarcoma: Examining real-world service utilization and outcomes.
11563 Background: Soft tissue sarcoma (STS) and its treatments frequently result in substantial physical morbidity, leadin...
Structural disparities in early-onset colorectal cancer mortality: A national county-level analysis.
10579 Background: Early-onset colorectal cancer (CRC) incidence and mortality are rising, with significant disparities by...
Real-world outcomes of olaparib with versus without bevacizumab in bevacizumab-naïve BRCA1/2-mutated ovarian cancer.
5574 Background: For patients with BRCA1/2-mutated epithelial ovarian, fallopian tube, or primary peritoneal cancer who co...
Attention-driven vision transformer analysis for automated melanoma diagnosis using dermoscopy.
e21532 Background: Melanoma is an aggressive skin cancer with rapidly rising incidence and disproportionately high mortali...
Intermittent fruquintinib plus trifluridine/tipiracil in refractory metastatic colorectal cancer (mCRC): A single-center, single-arm phase II study.
e15560 Background: A phase II study suggested that the combination of fruquintinib (Fru) and trifluridine/tipiracil (TAS-1...
Multimodal immune profile score (IPS) signature as a predictive response biomarker to immune checkpoint inhibitors in tumor mutational burden-high (TMB-H) advanced pancancer cohorts.
e14590 Background: Immune checkpoint inhibitors (ICI) have altered the oncology treatment landscape with improved outcomes...
Advancing equity in breast cancer biomarker testing: An updated study on hospital settings and patient involvement.
e13751 Background: Building on previous research, this updated study delves deeper into the persistent disparities in brea...
[ <sup>68</sup> Ga] Ga-NYM096 PET/CT in patients with primary and metastatic clear cell renal cell carcinoma: A preliminary study.
4537 Background: With limitations of conventional imaging and biopsy, accurate, non-invasive techniques to detect in patie...
Disparities in receipt of guideline-concordant adjuvant chemotherapy and survival outcomes among immigrant patients with colon cancer: Real-world evidence from Ontario.
1639 Background: Immigrants comprise a growing proportion of the Canadian population and may face unique barriers to acces...