Journal of Clinical Oncology
Articles in this Issue
Social risk factors and treatment preferences for patients with breast cancer.
e23139 Background: Physicians often overestimate their understanding of patient preferences. While patient preferences are...
Systematic review of non-oncologic interventions for neoplastic fever.
e24060 Background: Neoplastic fever (or “tumor fever”, TF), is a rare and challenging condition, notable for debilitating...
Real-world evidence on definitive chemoradiotherapy following neoadjuvant chemoimmunotherapy in locally advanced head and neck squamous cell carcinoma.
6094 Background: Real-world evidence regarding the efficacy and safety of neoadjuvant chemoimmunotherapy (NACI) in the tre...
Sedative-hypnotic use peri-chemotherapy and short-term fall and fracture risk in older adults with cancer.
e13765 Background: Falls and fractures are high-impact geriatric adverse events during chemotherapy. Sedative-hypnotics ar...
Long-term associations between ambient PM₂.₅ and PM₁₀ and lung cancer hospital admissions.
e20092 Background: Air pollution is a significant environmental health threat worldwide and an important modifiable risk f...
Rethinking the role of tumor size in bladder preservation: Comparing survival outcomes of radical cystectomy (RC) and tri-modality therapy (TMT).
4621 Background: TMT (maximal TURBT followed by chemoradiation) is typically reserved for bladder cancer (BC) patients wit...
Cell-free DNA (cfDNA) methylation-based multi-cancer early detection (MCED) assay to enable subtyping of lung cancer, breast cancer, and non-Hodgkin lymphoma (NHL).
3047 Background: Given that distinct pathological and molecular subtypes of most cancers correspond to different treatment...
Ultrasensitive circulating tumor DNA detection and molecular clearance as a prognostic and predictive marker in advanced renal cell carcinoma.
4551 Background: Renal cell carcinoma (RCC) is characterized by exceptionally low levels of circulating tumor DNA (ctDNA),...
Fraction genome altered to predict survival in early-stage non–small cell lung cancer.
8042 Background: Patients with stage I-III non-small cell lung cancer (NSCLC) often have very different outcomes, even whe...
Diabetic ketoacidosis and hyperosmolar hyperglycemic state as high-acuity phenotypes in U.S. cancer hospitalizations: National Inpatient Sample, 2018–2022.
e23197 Background: Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are uncommon but high-acuity eve...
CLDN18.2–targeting antibody-drug conjugate BA1301 in advanced solid tumors: Results from a phase I clinical trial.
4031 Background: Aberrant expression of claudin18.2 (CLDN18.2) has frequently been observed in various solid tumors, makin...
Do mental health disorders modify cytokine release syndrome risk in immune effector cell therapy? Full-cohort analysis with tarlatamab validation.
e19002 Background: Cytokine release syndrome (CRS) is a common immune effector cell (IEC) therapy toxicity. Host psychiatr...
Survival and treatment patterns of patients with metastatic urothelial cancer in France: Results of a cohort study using the French National Healthcare database (SNDS).
4610 Background: Despite the increasing number of available treatment options, metastatic urothelial cancer (mUC) remains...
Phase I trial of trastuzumab deruxtecan in combination with stereotactic radiosurgery for brain metastases from HER2-positive breast cancer.
TPS2093 Background: Brain metastases (BM) develop in nearly 40-50% of patients with HER2-positive breast cancer. Stereotac...
Association of facility type with overall survival in older adults with angioimmunoblastic T-cell lymphoma: A National Cancer Database analysis.
e19074 Background: Angioimmunoblastic T cell lymphoma (AITL) is a distinct and aggressive subtype of peripheral T cell lym...
Rituximab pre-conditioning in a phase I study of CARv3-TEAM-E for recurrent glioblastoma (GBM): The INCIPIENT trial.
2059 Background: Chimeric Antigen Receptor (CAR) T cells for glioblastoma (GBM) have been limited by the challenge of targ...
RAD-SG: Adaptive radiation therapy with concurrent sacituzumab govitecan for bladder preservation in patients (pts) with muscle invasive bladder cancer (MIBC).
e16614 Background: Concurrent chemoradiotherapy (CRT) is a bladder-preserving option for patients (pts) with MIBC but is l...
Phase II trial of asciminib for newly diagnosed chronic myeloid leukemia.
6589 Background: Asciminib is safe and effective across all lines of therapy of chronic myeloid leukemia (CML). Here, we r...
Tisagenlecleucel (tisa-cel) in pediatric and young adult patients with high-risk (HR) B-cell acute lymphoblastic leukemia (B-ALL) and minimal residual disease (MRD) at the end of frontline consolidation (EOC).
10000 Background: Persistent MRD portends a high risk of relapse in B-ALL. In the Children’s Oncology Group (COG)...
TIGOS-LS, an open-label, randomized study of BMS-986489 (atigotatug + nivolumab fixed-dose combination) vs durvalumab as consolidation therapy following chemoradiotherapy in limited-stage small-cell lung cancer.
TPS8134 Background: Durvalumab consolidation was added to concurrent chemoradiotherapy for standard-of-care treatment of l...
Racial demographic reporting in clinical trials supporting NCCN NSCLC guidelines.
e13739 Background: Non-Small Cell Lung cancer (NSCLC) demonstrates marked global racial and ethnic disparities in incidenc...
Mortality trends among U.S. adults with breast cancer and hypertensive diseases: A nationwide CDC WONDER analysis from 1999 to 2023.
e12716 Background: Hypertension is a well-established risk factor for cardiovascular mortality among cancer patients and m...
Stereotactic radiosurgery (SRS) alone vs SRS + whole-brain radiotherapy (WBRT) for 1–4 brain metastases: Meta-analysis of randomized controlled trials.
e14008 Background: Whether adding WBRT to SRS improves survival for patients with limited brain metastases remains controv...
Efficacy and safety of cadonilimab plus chemotherapy and bevacizumab as second-line treatment in patients with <i>RAS</i> -mutant metastatic colorectal cancer: Preliminary findings of a multi-center, single-arm study.
e15602 Background: To date, immune-checkpoint inhibitors remain ineffective for patients with proficient mismatch repair/m...
Acupuncture for psychoneurological symptoms in breast cancer: Symptom-specific response and sustainability.
e24067 Background: Breast cancer survivors receiving adjuvant endocrine therapy often endure persistent psychoneurological...