Journal of Clinical Oncology
Articles in this Issue
Circulating tumor DNA monitoring in peptide receptor radionuclide therapy–treated patients with gastroenteropancreatic neuroendocrine tumors.
e16321 Background: Circulating biomarkers such as chromogranin A (CgA) are commonly used in the management of gastroentero...
IDE892 as monotherapy and in combination with IDE397 in patients with 5-methylthioadenosine phosphorylase-deleted ( <i>MTAP</i> -Del) advanced solid tumors (IDE892001): Phase 1 trial.
TPS3182 Background: MTAP deletion in solid tumors causes intracellular accumulation of methylthioadenosine (MTA) which par...
Debio 0123 (zedoresertib), a selective WEE1 inhibitor, in combination with carboplatin in adult patients with platinum-resistant ovarian cancer: Expansion part of the Debio0123-101 phase 1 study.
e15154 Background: Debio 0123 is an oral, brain-penetrant, highly selective WEE1 inhibitor. WEE1 inhibition leads to S pha...
Clinical impact of routine MRI screening for brain metastasis in patients with breast cancer: A meta-analysis.
e14031 Background: Brain metastases (BM) are a frequent and clinically significant complication of metastatic breast cance...
Barriers and facilitators to multidisciplinary head & neck cancer care coordination in Tanzania.
e13567 Background: Tumor boards (TBs) are considered a standard of care for multidisciplinary, patient-centered cancer man...
Deep learning on routine histopathology to enable one-year survival prediction in pancreatic ductal adenocarcinoma.
e16016 Background: Pancreatic cancer ductal adenocarcinoma (PDAC) is an aggressive malignancy with a poor prognosis and li...
Phase 2 multicenter trial of chemoimmunotherapy for patients with neuroendocrine or aggressive variant metastatic prostate cancer (CHAMP).
5016 Background: Platinum-doublet chemotherapy is effective in pts with neuroendocrine small cell neuroendocrine or aggres...
Epidemiologic and clinicopathological characteristics of SMARCA4-deficient non–small cell lung cancer form a single center in Yunnan, China.
e20771 Background: SMARCA4-deficient non-small cell lung cancer (SMARCA4-d NSCLC) is an aggressive subtype with poorly def...
NCDB analysis of follicular adenocarcinoma, well-differentiated: Demographic and clinical outcomes.
e18134 Background: Follicular adenocarcinoma, well differentiated (FAWD), is a slow-growing cancer that originates in the...
Cocaine use disorder among hospitalized patients with non-Hodgkin’s lymphoma: A national study.
e19105 Background: Cocaine use disorder (CUD) continues to be a public health concern, with a documented global resurgence...
Physics-informed neural network–driven early assessment of PEG feeding tube placement prediction for head and neck cancer.
e18113 Background: Percutaneous endoscopic gastronomy (PEG) feeding tubes are placed in patients with head and neck (HN) c...
A multicenter single-arm phase II trial evaluating the safety and efficacy of panitumumab and irinotecan in patients with Neo <i>RAS</i> wild-type metastatic colorectal cancer (C-PROWESS trial).
3546 Background: Previous studies have demonstrated favorable efficacy of anti-epidermal growth factor receptor (EGFR) mon...
Patient preferences regarding bispecific antibody (BsAb) treatment schedules and clinical profiles in second-line or later (2L+) diffuse large B-cell lymphoma (DLBCL).
e23129 Background: Recent trials have examined BsAb combinations in 2L+ relapsed/refractory (R/R) DLBCL: glofitamab plus g...
Efficacy and safety of thoracic radiotherapy in metastatic non–small cell lung cancer during the immunotherapy era: A real-world study.
e20577 Background: The synergistic effect of immunotherapy combined with thoracic radiotherapy (TRT) in locally advanced n...
Expansion of a highly activated (HLA-DR+/CD38+) CAR T cell population after mezigdomide exposure post–idecabtagene vicleucel infusion in relapsed multiple myeloma.
7540 Background: Herein, we report CAR T subsets from peripheral blood (PB) mononuclear cell (PBMC) samples from the NCT06...
Efficacy of targeting replication stress in neuroblastoma.
3116 Background: Children with high-risk and relapsed neuroblastoma (NB) need improved therapies, and recurrent cytogeneti...
Adjuvant endocrine therapy omission in ER-positive breast cancer treated with neoadjuvant chemotherapy.
525 Background: Adjuvant endocrine therapy (ET) decreases breast cancer (BC) recurrence and improves overall survival (OS)...
Treatment patterns and PD-L1 testing among persistent, recurrent, or metastatic cervical cancer patients in the United States community oncology setting.
5522 Background: Pembrolizumab was approved for persistent, recurrent, or metastatic cervical cancer (PRM-CC) among patien...
Clinically significant immune-related adverse events with perioperative pembrolizumab in early triple-negative breast cancer: Analysis of trial and real-world evidence.
e12652 Background: Pembrolizumab plus chemotherapy improves pathologic complete response (pCR) and survival in early-stage...
Maintenance treatment with toripalimab and anlotinib after anthracycline-based chemotherapy in patients with advanced soft tissue sarcoma (TORANS): A single-arm, phase 2 trial.
11512 Background: To date, there is no established maintenance strategy for patients with advanced soft tissue sarcoma (ST...
Gender-based differences in malnutrition among patients with stage IV lung adenocarcinoma.
e22669 Background: Malnutrition, cachexia and weight loss are potential complications in patients with advanced lung cance...
Age and the genomic landscape of AML in precision oncology: An analysis using ASH HematOmics Program.
6543 Background: Age is a major determinant of prognosis and treatment selection in acute myeloid leukemia (AML), yet the...
Management of amivantamab-associated scalp toxicity: A multicenter retrospective cohort study.
e24207 Background: Scalp toxicities, namely erosive pustular dermatosis (EPD) and scalp folliculitis, are common and often...
Debriefing initiative on the oncology firm.
e21001 Background: Medical oncology is a core internal medicine residency rotation at Yale New Haven Hospital (YNHH). In a...
Bridging multi-omics to routine precision oncology: Biologically informed knowledge transfer for precision pCR prediction in neoadjuvant immunotherapy.
e12569 Background: Immune Checkpoint Inhibitors (ICI) significantly improve pCR rates, yet optimal patient selection is im...