Journal of Clinical Oncology
Articles in this Issue
Impact and prognosis of pembrolizumab combination in neoadjuvant chemotherapy for triple-negative breast cancer: A single-center retrospective study.
e12507 Background: The addition of pembrolizumab (PEM) to neoadjuvant chemotherapy (NAC) has been shown to significantly i...
Lung cancer stage prediction using longitudinal CT imaging compared with single-timepoint assessment.
8018 Background: Lung cancer staging guides treatment decisions but is based on single-timepoint imaging, treating tumors...
Change in relative cerebral blood volume as a biomarker for early response to bevacizumab in patients with recurrent glioblastoma: ECOG-ACRIN EAF151.
2016 Background: Bevacizumab therapy (Bev) for recurrent glioblastoma (rGBM) has not demonstrated improved overall surviva...
Spatial multiomic profiling to identify de-differentiated tumor phenotypes and exhausted T cell niches in rhabdoid and sarcomatoid RCC.
4557 Background: Rhabdoid and sarcomatoid (S/R) differentiation are high-grade dedifferentiated states that can arise acro...
Disparities in race and insurance status among hospitalized patients with pancreatic cancer and protein–energy malnutrition: A nationwide analysis, 2016–2022.
11052 Background: Protein–energy malnutrition (PEM) is frequently encountered in patients with pancreatic cancer and is as...
Effects of upfront dual immunotherapy on overall survival in patients with metastatic non-small cell lung cancer with no targetable mutations or PD-L1 expression.
e20588 Background: Upfront treatment decision for patients with metastatic Non-Small Cell Lung Cancer (NSCLC) with no targ...
Assessing breast density: Are convolutional neural networks the only path?
e12558 Background: Beyond reducing image interpretability, high breast density is an independent risk factor for breast ca...
Impact of Medicaid expansion on five-year mortality among patients with melanoma in the United States.
e21603 Background: Melanoma survival depends on early diagnosis and timely access to definitive surgery and modern systemi...
A phase 3 randomized, open-label study of pasritamig (JNJ-78278343), a T-cell engager targeting human kallikrein-2, with docetaxel versus docetaxel for metastatic castration-resistant prostate cancer.
TPS5139 Background: Metastatic castration-resistant prostate cancer (mCRPC) remains an incurable disease with high morbidi...
Treatment selection for first- and second-line therapy and survival outcomes in advanced biliary tract cancer: A large real-world retrospective analysis.
e16197 Background: Biliary tract cancer (BTC) is an aggressive malignancy with constrained therapeutic options. This study...
Postoperative adjuvant donafenib-based therapy for patients with hepatocellular carcinoma at high risk of recurrence.
e16256 Background: The 5-year recurrence rate after radical resection for hepatocellular carcinoma (HCC) is as high as 70%...
National burden of cholangiocarcinoma in the United States: A 20-year analysis of temporal trends and racial disparities (2005–2024).
e16493 Background: Cholangiocarcinoma (CCA) is an uncommon but highly lethal malignancy with rising global concern, yet lo...
Neoadjuvant immunotherapy combined with concurrent chemoradiotherapy for locally advanced esophageal squamous cell carcinoma: A prospective, single-arm, phase II trial.
e16095 Background: Concurrent chemoradiotherapy (CCRT) is the standard treatment for locally advanced esophageal squamous...
Interim analysis of TAD: A phase 2 single-arm open-label study of combination therapy of transarterial chemoembolization and ablation with durvalumab in unresectable hepatocellular carcinoma.
e16296 Background: Transarterial chemoembolization (TACE) combined with ablation has been used to treat unresectable hepat...
Inferring molecular signatures in colorectal cancer directly from routine whole-slide images.
3522 Background: Molecular profiling has advanced colorectal cancer (CRC) research but remains limited in the clinic due t...
Gaps in patient-facing information on artificial intelligence in cancer care: A cross-sectional analysis.
9000 Background: Artificial intelligence (AI) is increasingly integrated into cancer care and is also widely acces...
Impact of CAPOX combined with traditional Chinese medicine (TiaoPi AnChang Decoction) on disease-free survival in patients with stage III or high-risk stage II colorectal cancer: An updated report of a randomized, double-blind, placebo-controlled trial.
3645 Background: Colorectal cancer (CRC) at early and mid-stages has significantly different prognoses from advanced CRC....
Targeted sensorimotor training vs. general aerobic exercise for chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis.
e24175 Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting toxicity in breast cancer patients...
Real-world comparison of enzalutamide and darolutamide for non-metastatic castration-resistant prostate cancer: A multicenter retrospective study.
e17048 Background: Although enzalutamide and darolutamide share a common mechanism of action targeting the androgen recept...
Knowledge, attitude, and practices of residents towards venous thromboembolism prophylaxis among cancer patients at Quirino Memorial Medical Center.
e22552 Background: The risk of venous thromboembolism (VTE) is higher in individuals with cancer than in those without can...
Fern-EC-01 (BNT323-01): A phase 3 trial of trastuzumab pamirtecan (HER2 ADC) versus investigator’s choice of chemotherapy in patients with previously treated, HER2-expressing, recurrent endometrial cancer (EC).
TPS5645 Background: Despite advancements in frontline therapies for EC, treatment options for recurrent/refractory disease...
Updated efficacy and safety of first-line PD-1 inhibitors plus metronomic oral vinorelbine in elderly patients with advanced NSCLC.
e20590 Background: Elderly patients (≥70 years) with metastatic non-small cell lung cancer (NSCLC) face challenges with st...
Beyond survival: Longitudinal prognostication in glioblastoma using conditional survival—A population-based study.
2045 Background: Glioblastoma multiforme (GBM) carries a poor prognosis, and the initial survival projections provided at...
Clinicopathological analysis and therapeutic management of radiation-induced sarcomas of the head and neck: A single-center retrospective study.
e23537 Background: Radiation-induced sarcoma of the head and neck (RISHN) is a rare but devastating late toxicity of curat...
Clinical and genetic landscape of individuals evaluated in a CHIP cardiology clinic: A single-center experience, 2020 to 2025.
6593 Background: Despite growing observational data linking clonal hematopoiesis of indeterminate potential (CHIP) to adve...