Nature

Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III

Abstract Plants make complex and potent therapeutic molecules1,2, but sourcing these molecules from natural producers or through chemical synthesis is difficult, which limits their use in th...

Metabolic adaptations direct cell fate during tissue regeneration

Abstract Although cell-fate specification is generally attributed to transcriptional regulation, emerging data also indicate a role for molecules linked with intermediary metabolism. For exa...

Ancient DNA helps trace stinky Roman fish sauce to its source

How fast are you ageing? Ordinary brain scans reveal the pace

Stare into a whale’s colossal eye — June’s best science images

Obesity drugs made in China could power next wave of treatments

Arrests of scientists over smuggled samples add to US border anxiety

Mixed plastics turned into valuable chemicals

Ku limits RNA-induced innate immunity to allow Alu expansion in primates

Spin-qubit control with a milli-kelvin CMOS chip

Abstract A key virtue of spin qubits is their sub-micron footprint, enabling a single silicon chip to host the millions of qubits required to execute useful quantum algorithms with error cor...

Water abundance in the lunar farside mantle

Oncogenic fusions converge on shared mechanisms in initiating astroblastoma

In-line NMR guided orthogonal transformation of real-life plastics

Genome diversity and signatures of natural selection in mainland Southeast Asia

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity

Nanoplastic concentrations across the North Atlantic

Abstract Plastic pollution of the marine realm is widespread, with most scientific attention given to macroplastics and microplastics 1,2...

Human de novo mutation rates from a four-generation pedigree reference

Abstract Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five complementary short-read and long-read sequencing technologies, we phase...

Ultra-depleted mantle source of basalts from the South Pole–Aitken basin

Plastics pollution is surging — the planned UN treaty to curb it must be ambitious

Author Correction: Regulatory genomic circuitry of human disease loci by integrative epigenomics

Mapping the chemical complexity of plastics

Publisher Correction: The P-loop NTPase RUVBL2 is a conserved clock component across eukaryotes

Custom CRISPR–Cas9 PAM variants via scalable engineering and machine learning

Lack of evidence for the transitional cerebellar progenitor

Nanoplastics make up most of the plastic pollutants in the North Atlantic Ocean