Nature
Articles in this Issue
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation
Abstract Neurodegeneration shows regional and cell-type-specific patterns in ageing and disease 1 , but the underlying me...
Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair
Abstract During mammalian evolution, excitatory neurons in upper cortical layer 2 and layer 3 (L2/3) have shown a disproportionate expansion compared with other...
Gene regulatory landscape dissected by single-cell four-omics sequencing
Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist
Abstract CD4 + regulatory T cells (T reg cells) are essential for immune toleranc...
Twenty-first century emergence of alpine fire in Central African mountains
Somatic evolution following cancer treatment in normal tissue
Abstract The extent to which exogenous sources, including cancer treatment, contribute to somatic evolution in normal tissue remains unclear. Here we used high-d...
Specific combinations of human and viral genetic variants explain a cancer predisposition in southern China
Pristine Antarctic ice records the Solar System’s travels
Ice core reveals longest-ever continuous record of Earth’s climate
Dried to survive: desiccated tardigrades tolerate high heat
Elsevier vs Meta: first science publisher sues over scraped research papers
Surge in fake citations uncovered by audit of 2.5 million biomedical-science papers
World’s largest forest research agency faces severe cutback by Trump administration
Beyond GDP: 31 alternatives to the world’s favourite measure of economic health
World-leading climate centre takes Trump administration to court
Author Correction: Proteasome-guided haem signalling axis contributes to T cell exhaustion
Early-career researchers do more ‘disruptive’ science than veterans
J. Craig Venter obituary: maverick biotechnologist who sequenced the human genome
Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion
Author Correction: Multidimensional profiling of heterogeneity in supratentorial ependymomas
Foreshock-induced slip transients set mainshock nucleation timing
Abstract Foreshocks are sometimes observed before earthquakes 1–13 , yet their role in controlling rupture nucleation rem...
EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk
Structural energetics of cold sensitivity
Abstract Thermosensitive transient receptor potential (TRP) ion channels enable somatosensory nerve fibres to detect changes in our thermal environment over a wi...