A preserved TGFβ cytostatic response through DLD-mediated metabolic modulation undermines anti-TGFβ therapy in gastric cancer

Y Yi-Qian Pan Y Yi Han Z Zheng-Yu Qian X Xin-Yao Zhang T Ting-Ting Wang (Department of Basic Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University) Z Ze-Rong Cai H Huan Chen Y Yun Li K Kun Liao Y Yong-Qiang Zheng Y Yan-Yu Zhang Q Qi-Nian Wu H Hao-Xiang Wu T Tian Tian W Wenqi Chen (Shenzhen Key Laboratory for Cancer Metastasis and Personalized Therapy, Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital) Y Yue Chen (State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials) Z Zhao-Lei Zeng Z Ze-Xian Liu H Hai-Long Piao X Xin-Yuan Guan (Department of Clinical Oncology, The University of Hong Kong) R Rui-Hua Xu H Huai-Qiang Ju (Shenzhen Key Laboratory for Cancer Metastasis and Personalized Therapy, Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital)