Nature Communications
Articles in this Issue
Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome
Abstract DNA methylation at cytosine bases (5-methylcytosine, 5mC) is a heritable epigenetic mark regulating gene expression. While enzymes that metabolize 5mC are well-characterized...
Author Correction: Seasonal recurrence and modular assembly of an Arctic pelagic marine microbiome
Should we be careful with exercise in post-exertional malaise after long COVID?
Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP
Abstract Multidrug ABC transporters harness the energy of ATP binding and hydrolysis to translocate substrates out of the cell and detoxify them. While this involves a well-accepted alternat...
Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans
Highly selective upcycling of plastic mixture waste by microwave-assisted catalysis over Zn/b-ZnO
Virtual fragment screening for DNA repair inhibitors in vast chemical space
Abstract Fragment-based screening can catalyze drug discovery by identifying novel scaffolds, but this approach is limited by the small chemical libraries studied by biophysical experiments...
Strong and early monkeypox virus-specific immunity associated with mild disease after intradermal clade-IIb-infection in CAST/EiJ-mice
Abstract Monkeypox virus (MPXV) is a zoonotic poxvirus long endemic in West and Central Africa. Outbreaks, first the global spread of clade II outside Africa in 2022, and since 2023 the acce...
Efficient hybrid numerical modeling of the seismic wavefield in the presence of solid-fluid boundaries
Abstract Applying full-waveform methods to image small-scale structures of geophysical interest buried within the Earth requires the computation of the seismic wavefield over large d...
Non-AUG HIV-1 uORF translation elicits specific T cell immune response and regulates viral transcript expression
Agricultural fertilization significantly enhances amplitude of land-atmosphere CO2 exchange
iPSCs and iPSC-derived cells as a model of human genetic and epigenetic variation
GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection
Realizing four-electron conversion chemistry for all-solid-state Li||I2 batteries at room temperature
Abstract Rechargeable Li||I2 batteries based on liquid organic electrolytes suffer from pronounced polyiodides shuttling and safety concerns, which can be potentially tackled by the use of s...
Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling
Species-resolved profiling of antibiotic resistance genes in complex metagenomes through long-read overlapping with Argo
Cell enlargement modulated by GATA4 and YAP instructs the senescence-associated secretory phenotype
A biodegradable and restorative peripheral neural interface for the interrogation of neuropathic injuries
SGK1 drives hippocampal demyelination and diabetes-associated cognitive dysfunction in mice
Biochemical analyses of cystatin-C dimers and cathepsin-B reveals a trypsin-driven feedback mechanism in acute pancreatitis
Abstract Acute pancreatitis (AP) is characterised by self-digestion of the pancreas by its own proteases. This pathophysiological initiating event in AP occurs inside pancreatic acinar cells...
Resolving discrepancies between chimeric and multiplicative measures of higher-order epistasis
Abstract Epistasis - the interaction between alleles at different genetic loci - plays a fundamental role in biology. However, several recent approaches quantify epistasis using a chimeric f...