Nature Communications
Articles in this Issue
Assessing the success of marine ecosystem restoration using meta-analysis
Period-doubling in the phase dynamics of a shunted HgTe quantum well Josephson junction
Abstract The fractional AC Josephson effect is a discerning property of topological superconductivity in hybrid Josephson junctions. Recent experimental observations of missing odd Shapiro s...
Synthesis of nickel(II)-containing meso-edited phthalocyanine derivatives
Genome-scale CRISPRi screen identifies pcnB repression conferring improved physiology for overproduction of free fatty acids in Escherichia coli
Incoherent feedback from coupled amino acids and ribosome pools generates damped oscillations in growing E. coli
Non-reciprocal Coulomb drag between Chern insulators
Dopamine prediction error signaling in a unique nigrostriatal circuit is critical for associative fear learning
Abstract Learning by experience that certain cues in the environment predict danger is crucial for survival. How dopamine (DA) circuits drive this form of associative learning is not...
Mechanically deformable organic ferroelectric crystal with plasticity optimized by fluorination
β-Carotene alleviates substrate inhibition caused by asymmetric cooperativity
Abstract Enzymes are essential catalysts in biological systems. Substrate inhibition, once dismissed, is now observed in 20% of enzymes1 and is attributed to the formation of an unproductive...
Efficient and accurate framework for genome-wide gene-environment interaction analysis in large-scale biobanks
Substrates bind to residues lining the ring of asymmetrically engaged bacterial proteasome activator Bpa
Abstract Mycobacteria harbor a proteasome that was acquired by Actinobacteria through horizontal gene transfer and that supports the persistence of the human pathogen Mycobacterium tuberculo...
A genome-wide cross-trait analysis characterizes the shared genetic architecture between lung and gastrointestinal diseases
Programmed enhancement of endogenous iron-mediated lysosomal membrane permeabilization for tumor ferroptosis/pyroptosis dual-induction
PD-L1+ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models
Abstract Sepsis, a leading cause of death in intensive care units, is associated with immune alterations that increase the patients’ risk of secondary infections and mortality, so better und...
Dynamic in-situ reconstruction of active site circulators for photo-Fenton-like reactions
Large-scale biosynthetic analysis of human microbiomes reveals diverse protective ribosomal peptides
Mechanism of quiescent nanoplastic formation from semicrystalline polymers
Cell-cycle dependent DNA repair and replication unifies patterns of chromosome instability
Abstract Chromosomal instability (CIN) is pervasive in human tumours and often leads to structural or numerical chromosomal aberrations. Somatic structural variants (SVs) are intimat...
PIP2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9
Abstract The strict exchange of Na+ for H+ ions across cell membranes is a reaction carried out in almost every cell. Na+/H+ exchangers that perform this task are physiological homodimers, a...
Muscle-specific Ryanodine receptor 1 properties underlie limb-girdle muscular dystrophy 2B/R2 progression
PinMyMetal: a hybrid learning system to accurately model transition metal binding sites in macromolecules
A 2D hybrid perovskite ferroelectric with switchable polarization and photoelectric robustness down to monolayer
Abstract The continuous dimensional scaling of semiconductor and logic photoelectric device requires ferroelectrics to possess robust photoelectric activity and switchable polarization at th...
Scalable and efficient electrochemical bromination of arenes with Faradaic efficiencies surpassing 90%
Engineered circular guide RNAs enhance miniature CRISPR/Cas12f-based gene activation and adenine base editing
Scaling-up molecular logic to meso-systems via self-assembly
Abstract Due to the small size and biocompatibility of molecules, molecular logic-based computation is a gateway to the informational basis of life processes. Logic-based computation operate...