Nature Communications
Articles in this Issue
Pyridinium ylides as photocatalytic atom transfer reagents
An apical ring protein essential for conoid complex assembly and daughter cell formation in Toxoplasma gondii
Abstract In Toxoplasma gondii , the conoid complex consists of intraconoidal microtubules (ICMTs), preconoidal rings (PCR...
Structural insights into mechanisms of zinc scavenging by the Candida albicans zincophore Pra1
Abstract Candida albicans causes over 400,000 life-threatening, and an additional half a billion of mucosal infections annually. In response...
Discovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation
PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate
Abstract Vertebrate radial glia progenitors (RGPs) balance self-renewal and differentiation through asymmetric cell division (ACD), which involves unequal centro...
Concurrent warming, freshening and cessation of deep convection in the Labrador Sea raised its sea level to a record high
Abstract The Labrador Sea, a major North Atlantic carbon sink and source of ventilated intermediate-depth water masses, is a vital component of the global climate system. Since the 1...
Data-driven dynamic modeling for inverter-based resources using neural networks
Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex
Maternal histone methyltransferases antagonistically regulate autosomal random monoallelic expression (aRMAE) in C. elegans
Abstract Undefined epigenetic programs act to probabilistically silence individual autosomal alleles, generating unique individuals, even from genetic clones. Th...
Structure of an LGR dimer, an evolutionary predecessor of glycoprotein hormone receptors
Porin A and α/β-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis
Abstract Carrion’s disease is endemic to the South American Andes and is characterized by fatal hemolytic anemia. This neglected tropical disease is caused by...
Dynamical development of strength and stability of asteroid material under 440 GeV proton beam irradiation
Abstract Asteroid materials experience rapid thermoelastic and plastic stress evolution when subjected to high-energy irradiation – an effect that has not previously been captured th...
Germline polymorphisms in the immunoglobulin kappa and lambda loci underpinning antibody light chain repertoire variability
Abstract Variation in antibody (Ab) responses contributes to variable disease outcomes and therapeutic responsiveness, the determinants of which are incompletely understood. This stu...
Molecular mechanisms of CO2 mineralization on wetting nanoscale surfaces using molecular simulations and metadynamics
Capturing atomic wetting dynamics in real time
Abstract Atomic-scale wetting governs material formation at the nanoscale but remains poorly understood under confinement, where classical capillarity models fai...
Large-scale crustal growth driven by LIP magmatism during the Paleoproterozoic
Abstract The evolution of Earth’s continental crust is crucial for understanding geodynamics, climate regulation, and the origins of life. The Paleoproterozoic, marked by the Great O...
Regulating active hydrogen supply and intermediate binding for pH-universal H2O2 electrosynthesis at ampere-level current density
TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress
Abstract Peroxisomes are versatile organelles mediating energy homeostasis and redox balance. While peroxisome dysfunction is linked to numerous diseases, the mechanisms regulating p...
Wetland productivity and stability increase more with average plant size than with plant functional diversity
Avian GCGR-mediated continuous fat utilization offers perspectives for obesity treatment
The nucleobase guanine at the 3’-terminus of oligonucleotide RGLS4326 drives off-target AMPAR inhibition and CNS toxicity
Genome-wide gene-environment interaction study uncovers 162 vitamin D status variants using a precise ambient UVB measure
Abstract Vitamin D status is influenced by genetic and environmental factors—primarily sun exposure. Using satellite weather data, we estimated an ambient UVB do...
Reciprocal control of metabolic and chromatin regulators improves rice tolerance to heat
Unravelling the magnitude and drivers of PFAS trophic magnification: a meta-analysis
Rhizosheath inhabiting Massilia are linked to heterosis in roots of maize
Abstract Heterosis, or hybrid vigor, describes the superior performance of F 1 hybrids compared to parental inbreds. Whil...