Nature Communications
Articles in this Issue
Ocean driven retreat of the Northeast Greenland Ice Stream following the Last Glacial Maximum
Abstract The Northeast Greenland Ice Stream (NEGIS), the largest ice stream draining the Greenland Ice Sheet (GrIS), is losing mass at an accelerating rate due to atmospheric and oce...
Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2
Abstract Unconventional secretion of Fibroblast Growth Factor 2 (FGF2) is mediated by direct translocation across the plasma membrane. This process is initiated...
Installation of d3-methyl group to drugs by continuous-flow solid-phase synthesis
Kinetically controlled hetero-fusion is a systems-level behaviour of polymer nanoparticle populations
Abstract Particle fusion is key for establishing communication between biological components. For this reason, whole cell fusion plays a crucial role in many processes, including inf...
Mechanical confinement induces ferroptosis through mitochondrial dysfunction
Physics-informed transformers for electronic quantum states
Abstract Neural-network-based variational quantum states, particularly autoregressive models, are powerful tools for describing complex many-body wave functions. However, their perfo...
Securing interfacial cationic copper for acidic CO2 reduction to ethylene
The CTLH ubiquitin ligase substrates ZMYND19 and MKLN1 negatively regulate mTORC1 at the lysosomal membrane
Abstract Most Epstein–Barr virus-associated gastric carcinoma (EBVaGC) harbor non-silent mutations that activate phosphoinositide 3 kinase (PI3K) to drive downstream metabolic signal...
Forestalled phase separation as the precursor to stripe order
Abstract Stripe order is a prominent feature in the phase diagram of the cuprate superconductors and has been established as the lowest-energy state of the two-d...
Plasma-wakefield accelerator simultaneously boosts electron beam energy and brightness
Abstract High-energy particle colliders and X-ray free-electron lasers demand electron beams with qualities currently achieved only in kilometer-scale radio-frequency accelerators. P...
Metastable dual-defect states drive deep protonation for selective CO2 photomethanation
Tracing contrails within cirrus clouds and their climate effect
Chromatin accessibility in stem cells unveils progressive transcriptional alterations in myelodysplastic syndrome
Inverse design of stochastic, voxelated thermo-viscoelastic digital materials
Abstract Polymer material jetting enables the fabrication of voxelated, multi-material structures with material control at the microscale. However, current work often neglects viscoe...
Elimination of a neutrophil Pad4 byproduct restores stem cell–mediated bone regeneration in hyperglycemia
Benchmarking DNA foundation models for genomic and genetic tasks
Abstract The rapid evolution of DNA foundation models promises to revolutionize genomics, yet comprehensive evaluations are lacking. Here, we present a comprehensive, unbiased benchm...
Microbial-vulcanized organic-inorganic dual-modulated cobalt hydroxide for oxygen evolution reaction
Polynomial-time quantum Gibbs sampling for the weak and strong coupling regime of the Fermi-Hubbard model at any temperature
Abstract Quantum computers hold the potential to revolutionise the simulation of quantum many-body systems, with profound implications for fundamental physics and applications like m...
Unveiling the global urban virome through wastewater metagenomics
Role of thalamus in human conscious perception revealed by low-intensity focused ultrasound neuromodulation
Quantification and prediction of solidification textures under additive manufacturing conditions
Using metagenomics and whole-genome sequencing to characterize enteric pathogens across various sources in Africa
Abstract Foodborne diseases (FBDs) remain a major public health concern in low- and middle-income countries (LMICs), with the African region carrying the heavies...
Silicate chemical weathering disrupts the global patterns of phosphorus limitation
CYFIP1 governs the development of cortical axons by modulating calcium availability
Abstract The human CYFIP1 gene is linked to Autism Spectrum Disorder (ASD) and Schizophrenia (SCZ), both associated with brain connectivity defects and corpus ca...
NEK7 couples SDHB to orchestrate respiratory chain electron transport homeostasis that impedes liver fibrosis
Abstract The mode of electron transport in mitochondrial respiratory chain determines whether it generates energy or more reactive oxygen species (ROS), a key fo...