Nature Communications
Articles in this Issue
Cost-effectiveness of the ReDIRECT/counterweight-plus weight management programme to alleviate symptoms of long COVID
Abstract Long-term effects of COVID-19 infection, termed Long COVID (LC), are associated with reduced quality of life. Symptoms associated with overweight/obesity overlap with and may aggrav...
Observation of cavity-tunable topological phases of polaritons
Abstract Topological polaritons characterized by light-matter interactions have become a pivotal platform for exploring new topological phases of matter. Recent theoretical advances unveiled...
Unusual topological polar texture in moiré ferroelectrics
Abstract Topological polar textures in ferroelectrics have attracted significant interest for their potential applications in energy-efficient and high-density data storage and processing. A...
In-host evolution of Yersinia enterocolitica during a chronic human infection
Viruses hijack FPN1 to disrupt iron withholding and suppress host defense
Abstract Viruses rely on intracellular materials, including iron, to complete their life cycles and iron withholding may limit viral infections. However, the mechanisms through which viruses...
Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions
Abstract The canonical Alzheimer’s Disease (AD) pathological cascade posits that the accumulation of amyloid beta (Aβ) is the initiating event, accelerating the...
Atmospheric source of mercury to the ocean constrained by isotopic model
EZH2 loss promotes gastric squamous cell carcinoma
Non-C2 symmetric chiral ligand dictating allyl-allyl coupling
Cryo-EM structures of the E. coli Ton and Tol motor complexes
Abstract The Ton and Tol motor proteins use the proton gradient at the inner membrane of Gram-negative bacteria as an energy source. The generated force is trans...
Nanotwinned CrN ceramics with enhanced plasticity
Photo-controlled vacancies and conductivity within single crystals of silver chalcogenolate cluster-based MOFs
Stress granule assembly impairs macrophage efferocytosis to aggravate allergic rhinitis in mice
Abstract Cytoplasmic stress granules (SG) assemble in response to stress-induced translational arrest and are key signaling hubs orchestrating cell fate and regulating various physiological...
Generating combinatorial diversity via engineered V(D)J-like recombination in Saccharomyces cerevisiae
Abstract V(D)J recombination is integral to the development of antibody diversity and proceeds through a complex DNA cleavage and repair process mediated by several proteins, including recom...
Single-cell transcriptomics reveals BMP4-BMPR2 signaling promotes radiation resistance in hematopoietic stem cells following injury
BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma
Abstract Circadian disruption enhances cancer risk, and many tumors exhibit disordered circadian gene expression. We show rhythmic gene expression is unexpectedl...
Machine learning reveals genes impacting oxidative stress resistance across yeasts
Abstract Reactive oxygen species (ROS) are highly reactive molecules encountered by yeasts during routine metabolism and during interactions with other organisms...
A biomimetic multi-component subunit vaccine via ratiometric loading of hierarchical hydrogels
Cold-induced nucleosome dynamics linked to silencing of Arabidopsis FLC
Abstract Temperature influences nucleosome dynamics, and thus chromatin, to regulate gene expression. Such mechanisms underlie the epigenetic silencing of Arabid...
Immunogenicity and safety of mRNA-based seasonal influenza vaccines encoding hemagglutinin and neuraminidase
Abstract Current influenza vaccines induce immune responses to hemagglutinin (HA), a surface glycoprotein of seasonal influenza viruses, but have suboptimal effectiveness. mRNA vaccines may...