Nature Communications
Articles in this Issue
Genetic risk predicts adolescent mood pathology via sexual differentiation of brain function and physiological aging
Abstract Recent evidence challenged the traditional, categorical approach to sex differences, indicating that each human brain comprises a mosaic of features, some of which are more common a...
Cardiomyocyte-derived USP13 protects hearts from hypertrophy via deubiquitinating and stabilizing STAT1 in male mice
Mainstreaming the local climate zone framework for climate-resilient cities
Methylations with methanol via bioinspired catalytic C–O bond cleavage
Bioactive lipid mediator class switching regulates myogenic cell progression and muscle regeneration
DNA methylation protects cancer cells against senescence
Abstract Inhibitors of DNA methylation such as 5-aza-deoxycytidine are widely used in experimental and clinical settings. However, their mechanism of action is such that DNA damage i...
Amylopectin branch trimming and biosynthesis elucidated by the rice isoamylase ISA1-ISA2 heterocomplex
Biohybrid-based pyroelectric bio-denitrification driven by temperature fluctuations
A contra-steric chemoselective hydrometallation strategy with bulky NHC for catalytic asymmetric branched allylamine synthesis
Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia
Regional specialization of movement encoding across the primate sensorimotor cortex
Abstract The process by which the cerebral cortex generates movements to achieve different tasks remains poorly understood. Here, we leveraged the rich repertoire of well-controlled primate...
Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity
Neoadjuvant ARX788 plus pyrotinib versus trastuzumab, pertuzumab, docetaxel and carboplatin for HER2-positive breast cancer: a randomised phase 2b trial
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
Abstract A central process contributing to the phenotype of aging is cellular senescence. We recently identified the FOXO4 – p53 axis as pivotal in maintaining the viability of senescent cel...
Gears in chemical reaction networks for optimizing energy transduction efficiency
Abstract Similarly to gear systems in vehicles, most chemical reaction networks (CRNs) involved in energy transduction have at their disposal multiple transduction pathways, each characteriz...
Highly stable two-level current fluctuation in complex oxide heterostructures
Recyclable self-secreting autonomous healing dielectrics for millisecond water quality sensing
Perceived community alignment increases information sharing
Abstract It has been proposed that information sharing, which is a ubiquitous and consequential behavior, plays a critical role in cultivating and maintaining a sense of shared reality. Acro...
Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer
Abstract Castration-resistant prostate cancer is a heterogeneous disease with variable phenotypes commonly observed in later stages of the disease. These include...
Organometallic-type reactivity of stable organoboronates for selective (hetero)arene C−H/C-halogen borylation and beyond
Commitment of adipose-resident c-kit+ progenitors to brown adipocytes contributes to adipose tissue homeostasis and remodeling
Chiroptical switching and strong circularly polarized luminescence in peptide supramolecular assemblies
Collapse of the standard ferromagnetic domain structure in hybrid Co/Molecule bilayers
Abstract The interplay between Hund’s coupling, exchange interaction and magnetic anisotropy is responsible for a multitude of magnetic phases, ranging from conventional ferromagneti...
RFC1 regulates the expansion of neural progenitors in the developing zebrafish cerebellum
Self-organizing glycolytic waves tune cellular metabolic states and fuel cancer progression
Abstract Although glycolysis is traditionally considered a cytosolic reaction, here we show that glycolytic enzymes propagate as self-organized waves on the membrane/cortex of human...