Nature Communications
Articles in this Issue
Chemical circularization of in vitro transcribed RNA for exploring circular mRNA design
Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence
Abstract The rise of antibiotic-resistant pathogens, particularly gram-negative bacteria, highlights the urgent need for novel therapeutics. Drug-resistant infections now contribute to appro...
CO2 hydrogenation to HCOOH catalyzed by aqueous Pd needle assembly
Dynamic atomic-scale electron avalanche breakdown in solid dielectrics
Coherence in resonance fluorescence
Bioinspired Sulfo oxygen bridges optimize interfacial water structure for enhanced hydrogen oxidation and evolution reactions
Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma
Redox state of subducted sediments controls porphyry copper mineralization along the Tethyan belt
Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay
Abstract Legionella pneumophila, an intracellular bacterial pathogen, injects effector proteins into host cells to manipulate cellular processes and promote its survival and pro...
Notch activity is modulated by the aGPCR Latrophilin binding the DSL ligand in C. elegans
Abstract The Notch pathway is a highly conserved signaling cascade across metazoans that regulates numerous physiological processes, including cell proliferation, differentiation, and fate d...
Dislocation-assisted electron and hole transport in GaN epitaxial layers
Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis
Abstract Activity recognition in live-cell imaging is labor-intensive and requires significant human effort. Existing automated analysis tools are largely limited in versatility. We...
C. elegans sperm and oocytes differentially transmit diet-induced adaptations to their progeny
Endogenous tyrosinase-catalyzed therapeutics
Abstract Tyrosinase (TYR) catalyzes the two initial steps of melanin synthesis from tyrosine in various organisms. However, overproduction, accumulation, and abnormal reduction of melanin ca...
Highly parallel optimisation of chemical reactions through automation and machine intelligence
Abstract We report the development and application of a scalable machine learning (ML) framework (Minerva) for highly parallel multi-objective reaction optimisation with automated hi...
Interplay between large low-recombining regions and pseudo-overdominance in a plant genome
Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase
Abstract The human nucleoporin RanBP2/Nup358 interacts with SUMO1-modified RanGAP1 and the SUMO E2 Ubc9 at the nuclear pore complex (NPC) to promote export and disassembly of exporti...
Genomic diversity and structure of prehistoric alpine individuals from the Tyrolean Iceman’s territory
Abstract The Eastern Italian Alps played a crucial bridging role between Mediterranean and Northern alpine populations since Prehistory. However, few prehistoric individuals from that region...
Non-monotonic size-dependent exciton radiative lifetime in CsPbBr3 nanocrystals
Deep crustal deformation driven by reaction-induced weakening
Gut microbiota and brain-resident CD4+ T cells shape behavioral outcomes in autism spectrum disorder
Enhancing ferroelectric stability: wide-range of adaptive control in epitaxial HfO2/ZrO2 superlattices
Enhanced coordination interaction with multi-site binding ligands for efficient and stable perovskite solar cells
Abstract Conventional passivating ligands bind to perovskite surfaces through only a single active site, which not only creates a resistive barrier due to dense ligand packing but also restr...
Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior
Abstract The cell nucleus is a soft composite material with a shell-like nuclear cortex enclosing chromatin, comprised of roughly 2 meters of DNA and associated proteins. Assembling on and a...