Nature Communications
Articles in this Issue
From net-zero to zero-fossil in transforming the EU energy system
Abstract The EU climate neutrality goal requires a strong reduction in fossil fuel use. However, whether a complete phase-out is feasible and desirable remains u...
Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo
Abstract Altered activity of brown adipose tissue (BAT) contributes to obesity, insulin resistance, and cardiovascular disease. BAT secretes endocrine factors (“batokines”) that regu...
Integrated broadband and high-efficiency difference frequency generation
Airqtl dissects cell state-specific causal gene regulatory networks with efficient single-cell eQTL mapping
Abstract Single-cell expression quantitative trait loci (sceQTL) mapping offers a powerful approach for understanding gene regulation and its heterogeneity acros...
Magnetic reconnection in the plasma disk at 23 Jupiter radii
RoCK and ROI: single-cell transcriptomics with multiplexed enrichment of selected transcripts and region-specific sequencing
Abstract Single-cell profiling technologies allow exploring molecular mechanisms that drive development, health, and disease. However, current methods still fall short of profiling s...
Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates
Information advantage in sensing revealed by Fano-resonant Fourier scatterometry
Abstract Fano resonances in nanophotonic structures are attractive for sensing due to their ultanarrow resonant linewidths and high local fields. Conventional read out schemes rely o...
Self-assembly of hybrid 3D cultures by integrating living and synthetic cells
Abstract Self-assembly is a fundamental property of living matter that drives the three-dimensional organization of cell collectives such as tissues and organs. Here, the co-assembly...
A primary oseltamivir-resistant mutation in influenza hemagglutinin and its implications for antiviral resistance surveillance
Repurposing clinically safe drugs for DNA repair pathway choice in CRISPR genome editing and synthetic lethality
Abstract We evaluate the effect of most FDA-approved drugs (>7,000 conditions) on double-strand DNA break repair pathways by analyzing mutational outcomes in human induced pluripo...
C-F bond integration in polymeric carbon nitride enables oxygen-tolerant photocatalytic reduction of NO to N2
Percolation transition in entangled granular networks
Pla2g7 regulates bone homeostasis via Alox12/12-HETE/Gpr31 signaling axis
Structural insights into clonal restriction and diversity in T cell recognition of two immunodominant SARS-CoV-2 nucleocapsid epitopes
Decomposition causes short-term increases in functional molecular diversity of dissolved organic matter
A generalized approach for enhancing contact-electro-catalysis of oxides in a broad temperature range by fluorination
Ultrahigh current output performance in piezoelectric energy harvesters enabled by phase boundary–bandgap synergistic engineering
Multiplex serology reveals age-specific immunodynamics of respiratory pathogens in the wake of the COVID-19 pandemic
Protection of metal interfaces against hydrogen-assisted cracking
Abstract Enabling a hydrogen economy requires the development of materials resistant to hydrogen embrittlement (HE). More than 100 years of research have led to several mechanisms an...
Photo-reversible amyloid nanoNETs for regenerative antimicrobial therapies
Abstract Drug-resistant bacterial infections, exacerbated by antibiotic resistance and biofilm resilience, disrupt tissue repair through dysregulated inflammatio...
All-metallic magnetic Purcell enhancement in a thermally stable room-temperature maser
Abstract Enhancing the spontaneous and stimulated emission rates of magnetic quantum emitters through the Purcell effect is essential for designing high-performa...
Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis
Abstract Ulcerative colitis (UC) is associated with epithelial metabolic derangements which exacerbate gut inflammation. Here, we develop colon organoid (colonoid) lines from pediatr...