Nature Communications
Articles in this Issue
PABPC1 SUMOylation enhances cell survival by promoting mitophagy through stabilizing U-rich mRNAs within stress granules
Author Correction: An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano
RNAi epimutations conferring antifungal drug resistance are inheritable
Abstract Epimutations modify gene expression and lead to phenotypic variation while the encoding DNA sequence remains unchanged. Epimutations mediated by RNA int...
Efficacy of modified-vaccinia Ankara vaccine as pre- and post-exposure prophylaxis against monkeypox sexual transmission in non-human primate model
The efficacy and safety of inhaled peptide YKYY017 for COVID-19 patients with mild illness: a phase 2 randomized controlled trial
Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential
Abstract Red blood cells and platelets derive from bi-potential bone marrow megakaryocyte-erythroid progenitors, but their study is constrained by cell scarcity and limited experimental syst...
Effervescence in a binary mixture with nonlinear non-reciprocal interactions
Abstract Non-reciprocal interactions between scalar fields that represent the concentrations of two active species are known to break the parity and time-reversal (PT) symmetries of the equi...
Urinary Complement proteome strongly linked to diabetic kidney disease progression
Iterative SCRaMbLE for engineering synthetic genome modules and chromosomes
Abstract Saccharomyces cerevisiae is closing-in on the first synthetic eukaryotic genome with genome-wide redesigns, including LoxPsym site i...
Mechanistic analysis and kinetic profiling of Soai’s asymmetric autocatalysis for pyridyl and pyrimidyl substrates
Abstract Nonlinear effects in chemical reactions, coupled with amplifying catalysis, can lead to remarkable phenomena like spontaneous symmetry breaking, central to the origin of biological...
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target
Abstract T-cell exhaustion contributes to immunotherapy failure in chronic lymphocytic leukemia (CLL). Here, we analyze T cells from CLL patients’ blood, bone marrow, and lymph nodes, as wel...
Photosynthate distribution determines spatial patterns in the rhizosphere microbiota of the maize root system
Abstract The spatial variation and underlying mechanisms of pattern formation in the rhizosphere microbiome are not well understood. We demonstrate that specific patterns in the distribution...
Safety and Immunogenicity of aerosolized adenovirus-vectored COVID-19 vaccine and intramuscular mRNA vaccine bivalent boosters: a randomized open-label clinical trial
Frequency-selective actuation of liquid crystalline elastomer actuators with radio-frequency
Abstract Soft and miniaturized robots possess the capability to operate inside narrow, confined environments. However, powering soft robots inside these environments with on-board batteries...
The HM-TARGET personalised real-time haemodynamic targets in critical care
Interfaces govern the structure of angstrom-scale confined water solutions
Abstract Nanoconfinement of aqueous electrolytes is ubiquitous in geological, biological, and technological contexts, including sedimentary rocks, water channel proteins, and applications li...
Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression
Abstract The growth of a tumor is tightly linked to the distribution of its cells along a continuum of activation states. Here, we systematically decode the activation state architec...
Author Correction: The role of charge in microdroplet redox chemistry
Switchable electrochemical pathways for the selective C(sp3)-Ge bond formation
How thoughtful experimental design can empower biologists in the omics era
Self-sustained frictional cooling in active matter
Abstract Cooling processes in nature are typically generated by external contact with a cold reservoir or bath. According to the laws of thermodynamics, the final temperature of a system is...
Quarter- and half-filled quantum Hall states and their topological orders revealed by daughter states in bilayer graphene
Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model
Abstract Cerebral malaria is a severe neurovascular complication of Plasmodium falciparum infection, with high mortality...