Nature Communications
Articles in this Issue
Worldwide genetic diversity of Plasmodium vivax Pv47 is consistent with natural selection by anopheline mosquitoes
Abstract Pv47 is the Plasmodium vivax ortholog of Pfs47, a protein that allows the Plasmodium falciparum malaria parasite to evade mosquito immunity and adapt to diverse vectors. We analyzed...
Molecularly resolved mapping of heterogeneous ice nucleation and crystallization pathways using in-situ cryo-TEM
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge
Abstract Diffusion-weighted MRI is critical for diagnosing and managing ischemic stroke, but variability in images and disease presentation limits the generalizability of AI algorithms. We p...
Lattice-matched antiperovskite-perovskite system toward all-solid-state batteries
Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients
Single-molecule tweezers decode hidden dimerization patterns of membrane proteins within lipid bilayers
Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy
Abstract Mutations that disrupt the clearance of damaged mitochondria via mitophagy are causative for neurological disorders including Parkinson’s. Here, we identify a Mitophagic Str...
High-dimensional one-shot optical field compressive sensing of structured light
Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function
Abstract Guanidine is a protein denaturant that is a widely used constituent in explosives, plastics, and resins. Its effects on muscle contraction were initially reported in 1876, which eve...
A multivalent mRNA vaccine elicits robust immune responses and confers protection in a murine model of monkeypox virus infection
Vaccination with Acinetobacter baumannii adhesin Abp2D provides protection against catheter-associated urinary tract infection
Heat transfer in metallic nanometre-sized gaps
The South American MicroBiome Archive (saMBA): enriching the microbiome field by studying neglected populations
Abstract The human gut microbiome is associated with numerous health outcomes, often in a region-specific manner. Unfortunately, global microbiome research remains profoundly imbalanced: ove...
Nucleophilic addition promoted ring rearrangement-aromatization in aza-/thio-sesquiterpenoid biosynthesis
Design of Ig-like binders targeting α-synuclein fibril for mitigating its pathological activities
Effect of intrapartum azithromycin on early childhood gut mycobiota development: post hoc analysis of a double-blind randomized trial
Abstract Intrapartum azithromycin prophylaxis reduced maternal infections but showed no effect on neonatal sepsis and mortality. Although antibiotic exposure may indirectly alter the mycobio...
Highly customizable, ultrawide-temperature free-form flexible sensing electronic systems based on medium-entropy alloy paintings
Mitigating emissions and costs through demand-side solutions in Chinese residential buildings
Evidence triangulator: using large language models to extract and synthesize causal evidence across study designs
Glial reactivity and cognitive decline follow chronic heterochromatin loss in neurons
Abstract In aging cells and animal models of premature aging, heterochromatin loss coincides with transcriptional disruption including the activation of normally silenced endogenous...
Early Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer’s disease
Abstract Alzheimer’s disease (AD) often begins with non-cognitive symptoms such as olfactory deficits, which can predict later cognitive decline, though the mech...
Regional heterogeneity of the blood-brain barrier
Abstract The blood-brain barrier (BBB), formed by specialized endothelial cells (ECs), regulates the extracellular composition of the central nervous system (CNS). Little is known about whet...
Development of conformation-selective antibodies targeting human SLC15A4
Lipid-mediated gating of a miniature mechanosensitive MscS channel from Trypanosoma cruzi
Abstract The mechanosensitive channel of small conductance (MscS) from E. coli (EcMscS) has served as the prevailing model system for understanding mechanotransduction in ion channels. Trypa...