Nature Communications
Articles in this Issue
Hierarchical luminescence center coupling enables time-dependent phosphorescence color from self-protective carbonized polymer dots
Targeted gene editing and near-universal cDNA insertion of CYBA and CYBB as a treatment for chronic granulomatous disease
Abstract Chronic granulomatous disease (CGD) is a severe inborn error of immunity caused by NADPH oxidase defects. Here, we develop CRISPR/Cas9-based gene editing strategies for correction o...
On-chip integration of achromatic metalens arrays
Time cell sequences during delay intervals are not dependent on brain state and do not support hippocampus-dependent working memory
Abstract Working memory (WM) is essential for performing cognitive tasks, and sequentially active hippocampal cells over many seconds (‘time cells’) have been observed during WM retention. T...
Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability
Abstract DNA transactions introduce torsional constraints that pose an inherent risk to genome integrity. While topoisomerase 1 (TOP1) activity is essential for DNA supercoil removal...
High-throughput micro-scale bandgap mapping for perovskite-inspired materials with complex composition space
Abstract To realize the full promise of high-throughput experimental workflows, the rate of sample synthesis must be matched by that of characterization. Of growing interest are contactless...
25 nm-Feature, 104-aspect-ratio, 10 mm2-area single-pulsed laser nanolithography
Structure guided functional analysis of the S. cerevisiae Mre11 complex
COUP-TFII-mediated reprogramming of the vascular endothelium counteracts tumor immune evasion
Abstract T cell scarcity in tumor tissues poses a critical challenge to cancer immunotherapy. Here we manipulate the tumor vasculature, an essential regulator of immune cell trafficking, to...
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants
Abstract The mosquito Aedes aegypti is the primary vector for dengue virus (DENV), which infects millions of people annually. Variability in DENV susceptibility among wild Ae. aegypti popula...
Recent community warming of moths in Finland is driven by extinction in the north and colonisation in the south
Abstract As the climate warms, species are shifting their ranges to match their climatic niches, leading to the warming of ecological communities (thermophilisation). We currently have littl...
Skillful subseasonal soil moisture drought forecasts with deep learning-dynamic models
Catalyst-free Ullmann coupling in aqueous microdroplets
Nitrogen and CO2 enrichment interact to decrease biodiversity impact on complementarity and selection effects
Abstract Global environmental change is causing a decline in biodiversity with profound implications for ecosystem functioning and stability. It remains unclear how global change factors int...
Sustainable DNA-polysaccharide hydrogels as recyclable bioplastics
Abstract Traditional petrochemical-derived plastics are challenging to recycle and degrade, and the existing (re)process methods are organic solvent-based and/or energy-intensive, resulting...
Unraveling the dynamics of conductive filaments in MoS2-based memristors by operando transmission electron microscopy
Abstract Advanced operando transmission electron microscopy (TEM) techniques enable the observation of nanoscale phenomena in electronic devices during operation. Here, we investigated later...
Screening and dissecting electroorganic synthesis by mass spectrometry decoupling of electrode and homogeneous processes
Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious
Abstract Flavivirus assembly is driven by the envelope glycoproteins pre-membrane (prM) and envelope (E) in the neutral pH environment of the endoplasmic reticulum. Newly budded, spiky parti...