Nature Communications
Articles in this Issue
Microglial replacement in a Sandhoff disease mouse model reveals myeloid-derived β-hexosaminidase is necessary for neuronal health
Abstract Lysosomal storage disorders (LSDs) are a large disease class involving lysosomal dysfunction, often resulting in neurodegeneration. Sandhoff disease (SD) is an LSD caused by a defic...
Hypoxic stress incites HIF1α-driven ribosome biogenesis that can be exploited by targeting RNA Polymerase I
Magic cancellation point for vibration resilient ultrastable microwave signal synthesis
Abstract Photonically-synthesized microwave signals have surpassed the phase-noise performance achievable by traditional means of RF signal generation. However, for microwave-photonic oscill...
Generative emergence of non-local representations in the hippocampus
Abstract The role of internally-generated network dynamics in rapid temporal sequence coding, updating, and parallel recalling of alternate spatial and mental navigation contexts has remaine...
Highly efficient all-perovskite photovoltaic-powered battery with dual-function viologen for portable electronics
Remodeling adipocytes’ lipid metabolism with a polycation loaded enzyme-active framework reverses osteoporotic bone marrow
Publisher Correction: Functional interplay between condensin I and topoisomerase IIα in single-molecule DNA compaction
Splicing QTL mapping in stimulated macrophages associates low-usage splice junctions with immune-mediated disease risk
Abstract The majority of immune-mediated disease (IMD) risk loci are located in non-coding regions of the genome, making it difficult to decipher their functional effects in relevant physiol...
Reprogramming the tumor microenvironment with c-MYC-based gene circuit platform to enhance specific cancer immunotherapy
CD99-mediated immunological synapse formation potentiates CAR-T cell function
Uncapping energy transfer pathways in metal-organic frameworks through heterogeneous structures
All-flexible chronoepifluidic nanoplasmonic patch for label-free metabolite profiling in sweat
Abstract Wearable sensors allow non-invasive monitoring of sweat metabolites, but their reliance on molecular recognition elements limits both physiological coverage and temporal res...
Mechanism and function of GPR3 regulated by a negative allosteric modulator
Invariant inter-subject relational structures in high order human visual cortex
ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice
Addition of longer wavelength absorbing chlorophylls into crops could increase their photosynthetic productivity by 26%
Self-healing Cu single-atom catalyst for high-performance electrocatalytic CO2 methanation
Response splicing quantitative trait loci in primary human chondrocytes identify putative osteoarthritis risk genes
Dopaminergic signaling regulates microglial surveillance and adolescent plasticity in the mouse frontal cortex
Abstract Adolescence is a sensitive period for frontal cortical development and cognitive maturation, marked by heightened structural plasticity in the dopaminergic (DA) mesofrontal...
Non-equilibrium critical scaling and universality in a quantum simulator
Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming
Spatial isotope deep tracing deciphers inter-tissue metabolic crosstalk
Efficient conversion of polyethylene to light olefins by self-confined cracking and reforming
Adsorbed oxygen dynamics at forced convection interface in the oxygen evolution reaction
Ultrafast decoupling of polarization and strain in ferroelectric BaTiO3
Abstract A fundamental understanding of the interplay between lattice structure, polarization and electrons is pivotal to the optical control of ferroelectrics....