Nature Communications
Articles in this Issue
Comparison of imaging based single-cell resolution spatial transcriptomics profiling platforms using formalin-fixed paraffin-embedded tumor samples
Programmable circuits for analog matrix computations
Physical vitrification and nanowarming at liter-scale CPA volumes: toward organ cryopreservation
Abstract Organ banking via vitrification could transform transplantation, but has never been achieved at human organ scales. This study tested vitrification and rewarming in 0.5–3 L...
Harnessing indole scaffolds to identify small-molecule IRE1α inhibitors modulating XBP1 mRNA splicing
Abstract The inositol-requiring enzyme 1 alpha (IRE1α) is an important sensor protein with dual kinase and ribonuclease function. It induces X-box binding protein 1 (XBP1) mRNA splicing and...
Nonreciprocal field theory for decision-making in multi-agent control systems
Abstract Field theories for complex systems traditionally focus on collective behaviours emerging from simple, reciprocal pairwise interaction rules. However, many natural and artificial sys...
Single-photon dual-comb ghost imaging spectroscopy
Auto-oscillations and directional magnon emission induced by spin current injection into large magnetic volumes
An sp-sp2-hybridized molecular carbon allotrope C16 flake
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation
Multimodal super-resolution: discovering hidden physics and its application to fusion plasmas
CD137L promotes immune surveillance in melanoma via HLTF regulation
Decoding structural transitions from CdSe nanoclusters to quantum dots through dynamic nuclear polarization NMR
Noise-induced quantum synchronization with entangled oscillations
Abstract Random fluctuations can lead to cooperative effects in complex systems. We here report the observation of noise-induced quantum synchronization in a chain of superconducting transmo...
Spurious precision in meta-analysis of observational research
Abstract Meta-analysis assigns more weight to studies with smaller standard errors to maximize the precision of the overall estimate. In observational settings, however, standard errors are...
RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets
Abstract The computational analysis of large proteomics datasets from gradient profiling or spatially resolved proteomics is often as crucial as experimental design. We present RAPDOR, a too...
MXene-configured graphite towards long-life lithium-ion batteries under extreme conditions
Impacts of urban and cropland expansions on natural habitats in Southeast Asia
Advances in biomonitoring technologies for women’s health
Abstract In global healthcare systems, sex and gender biases have favored cisgender males, which has led women and transgender individuals to be understudied and underrepresented in medical...
Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked Parkinson’s disease and dementia with Lewy bodies
Vibrationally-dependent molecular dynamics in mutual neutralisation reactions of molecular oxygen ions
Abstract Product distributions and dynamics of low-collision-energy mutual neutralisation reactions involving even simple molecular ions are largely unknown. Rea...
Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats
Abstract Cataract caused by crystallin aggregation is the leading cause of vision impairment and blindness globally. The only available treatment option so far is surgery. In this study, we...
VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior
Abstract The ventral tegmental area (VTA) dopamine neurons have been implicated in diverse behaviors. These VTAdopamine neurons are intermixed with neurons that co-transmit glutamate and GAB...