Nature Communications
Articles in this Issue
A basic framework to explain splice-site choice in eukaryotes
Abstract Changes in splicing can mediate phenotypic variation, ranging from flowering time differences in plants to genetic diseases in humans. Splicing changes occur due to differences in s...
Sustainable electromagnetic interference shielding materials from cellulose-grafted n-type polymers
Age-related constraints on the spatial geometry of the brain
Abstract Age-related structural brain changes may be better captured by assessing complex spatial geometric differences rather than isolated changes to individual regions. We applied an anal...
RNA polymerase II is a polar roadblock to a progressing DNA fork
Abstract Transcription–replication conflicts threaten genome stability. Although head-on conflicts are more detrimental and prone to R-loop formation than co-directional conflicts, the cause...
Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia
Long-term homeostasis in microbial consortia via auxotrophic cross-feeding
Disentangling dispersion from mean reveals true heterogeneity-diversity relationships
Abstract Understanding the effect of heterogeneity is fundamental to numerous fields. In community ecology, classical theory postulates that habitat heterogeneity determines niche dimensiona...
Isoprene chemistry under upper-tropospheric conditions
Abstract Isoprene (C5H8) is the non-methane hydrocarbon with the highest emissions to the atmosphere. It is mainly produced by vegetation, especially broad-leaved trees, and efficiently tran...
Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus
Prolonged glucagon exposure rewires lipid oxidation and drives diabetic kidney disease progression
The spatial complexity of optical computing: toward space-efficient design
Fully chemical interface engineering for statically and dynamically stable perovskite solar cells
Abstract The interfacial modifications between perovskite and charge-transport layers can arise from strong chemisorption bonds or weak physical adsorption interactions. However, modificatio...
Aligning global mercury mitigation with climate action
Privacy preserving optimization of communication networks
The zebra finch auditory cortex reconstructs occluded syllables in conspecific song
Circular RNA-based protein replacement therapy mitigates osteoarthritis in male mice
Aging and memory of transitional turbulence
Abstract The recent classification of the onset of turbulence as a directed percolation (DP) phase transition has been applied to all major shear flows including pipe, channel, Couette and b...
Diaphragm-based carbon monoxide electrolyzers for multicarbon production under alkaline conditions
Abstract Transforming waste carbon into valuable fuels and chemicals is a key step toward sustainable manufacturing. One promising approach is the electrochemica...
Schottky engineering of GDYO@Pt to boost piezoelectric and oxidative stress modulation for accelerated cranial regeneration
EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers
Abstract Exonuclease EXO1 performs multiple roles in DNA replication and DNA damage repair (DDR). However, EXO1 loss is well-tolerated, suggesting the existence of compensatory mechanisms th...
Supercurrent time division multiplexing with solid-state integrated hybrid superconducting electronics
Electronic Hong Ou Mandel interferences to unveil the 2/3 fractional quantum Hall edge channel dynamics
Biomimetic fibrous semiconducting micromesh via tuning phase separation for high-performance stretchable optoelectronic synapses
Abstract Polymer semiconductors hold great potential for next-generation bionic devices, due to their inherent flexibility and biocompatibility. However, endowing them both robust mechanical...
Estimating disorder probability based on polygenic prediction using the BPC approach
Abstract Polygenic Scores (PGSs) summarize an individual’s genetic propensity for a given trait. Bayesian methods, which improve the prediction accuracy of PGSs, are not well-calibrated for...
Cryo-EM reveals evolutionarily conserved and distinct structural features of plant CG maintenance methyltransferase MET1
Abstract DNA methylation is essential for genomic function and transposable element silencing. In plants, DNA methylation occurs in CG, CHG, and CHH contexts (where H = A, T, or C), with the...