Nature Communications
Articles in this Issue
Rapid monitoring of global land change
The genomic landscape of relapsed infant and childhood KMT2A-rearranged acute leukemia
Abstract To study the mechanisms of relapse in KMT2A-rearranged (KMT2A-r) acute lymphoblastic (ALL) and acute myeloid leukemia (AML), we performed whole-genome and exome sequencing of infant...
Supercritical CO2-assisted rapid synthesis of covalent organic framework-based electrocatalyst for efficient two-electron oxygen reduction reaction
Abstract Covalent organic frameworks (COFs) hold significant promise as electrocatalysts, but their synthesis is typically constrained by prolonged reaction times (>72 h), high temperatur...
Synthesis, reactivity and nucleophilicity of carboranyl-B-Mg compound
Tailoring Cas12a functionality with a user-friendly and versatile crRNA variant toolbox
Global phylogeny and taxonomy of Artemisia
Abstract Developing robust phylogenies and comprehensive taxonomies for big plant genera is crucial for unlocking plant-derived solutions to global sustainability challenges. Artemisia, a bi...
Supramolecular networks with high shear stiffening enabled by metal ion-mediated hydrogen bonding enhancement strategy
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer
Abstract Metastatic castration-resistant prostate cancer (mCRPC) is a lethal disease requiring additional therapeutic strategies. MCL1, an anti-apoptotic BCL2 family member, promotes cancer-...
Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
Nonequilibrium chemical short-range order in metallic alloys
Cryo-EM structure of the yeast Saccharomyces cerevisiae SDH provides a template for eco-friendly fungicide discovery
Accelerated dissolution of iridium anode in the presence of organic compounds
Node role of wild boars in virus circulation among wildlife and domestic animals
Local crystallization inside the polymer electrolyte for lithium metal batteries observed by operando nanofocus WAXS
Abstract The development of next-generation lithium-based batteries is accompanied by the intention to suppress the formation of dendritic lithium on the electrode, and is dominated by the p...
Squaric acid-based zwitterionic covalent organic framework induces triple synergy for boosted hydrogen peroxide photosynthesis
Defect-engineered black tetragonal-tungsten-bronze ferroelectric crystal for full spectrum absorption and broadband photoelectronic conversion
A concurrently optimization of H and OH binding energies in atomically Ni anchored Ru/RuO2 nanosheet driving high CO-tolerant hydrogen oxidation catalysis
Demethylation of methylguanidine by a stepwise dioxygenase and lyase reaction
Abstract Guanidine-responsive riboswitches control genes that enable either detoxification or assimilation of guanidino compounds. In Vreelandella boliviensis and other halophilic bacteria,...
Fosl2 facilitates chromatin accessibility to determine developmental events during follicular maturation
Abstract Granulosa cells (GCs) are the most dynamically responsive cell lineage to encourage continuous folliculogenesis; however, developmental dynamics and interplay with downstream transc...
Characterization of prevalent genetic variants in the Estonian Biobank body-mass index GWAS
Abstract Population-specific genome-wide association studies can reveal high-impact genomic variants that influence traits like body-mass index (BMI). Using the...
A scope of prebiotic neat reaction conditions and the mechanism of urea-assisted phosphorylations of alcohols
Abstract Two theories of the origin of life on Earth, one located in the Hadean seafloor, the other on the surface of subaerial landmasses and basins, need reconcilement. Natural ene...
Metabolic profiling reveals channeled de novo pyrimidine and purine biosynthesis fueled by mitochondrially generated aspartic acid in cancer cells
Selective HLA knockdown and PD-L1 expression prevent allogeneic CAR-NK cell rejection and enhance safety and anti-tumor responses in xenograft mice
Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer
Abstract The aggressiveness of prostate cancer is primarily assessed from histopathological data using the Gleason scoring system. Conventional artificial intelligence (AI) approaches can pr...