Nature Communications
Articles in this Issue
Machine learning-assisted self-powered ear tag for animal welfare
Structural basis for uracil removal from DNA by human SMUG1
Abstract Human single-strand-selective monofunctional uracil DNA glycosylase 1 (hSMUG1) removes uracil, 5-hydroxymethyluracil (5hmU) and 5-fluorouracil (5FU) from DNA, thereby initia...
A tunable Cas12a platform for single-cell perturbation screening and CRISPRi
Room-temperature multistage metastability in a moiré superstructure
Abstract Charge density waves (CDWs) offer versatile platforms for accessing metastable states due to their sensitivity to external stimuli. However, most metast...
Learned statistical regularity modulates anticipatory micro-saccades toward suppressed distractor locations
A Rras2–BMPR2 feedback loop sustains osteogenesis and represents a therapeutic target for osteoporosis
Generative modelling of inorganic materials with explicit electronic structure
Tailoring polymers of intrinsic microporosity as photoredox catalysts for continuous-flow reaction–separation processes
HPV16 genetic variation provides evidence of positive natural selection driven by HLA class I
Abstract Human papillomavirus type 16 (HPV16) causes more cancer than any other virus. However, most HPV16 infections are controlled by the host’s immune system...
An agent-based platform for simulating the impact of chlamydia vaccine in the US population
Competing structural orders frustrate crystallization in a metallic glass
An intelligent feedback loop for sustaining self-lubrication and wear resistance
Abstract Intelligent materials that self-sense and self-adjust are an emerging frontier in sustainable technology. Here we introduce a Cu/C nanocomposite film th...
Cross-species transcriptomic analysis of rodent model fidelity to human mesial temporal lobe epilepsy
MINTsC learns multi-way chromatin interactions from single cell high throughput chromatin conformation data
Stress-induced ribosome degradation in Bacillus subtilis is mediated by the RNase Y-specificity complex
Abstract Limiting ribosome synthesis and activity is crucial for adaptation to stresses, such as heat or nutrient starvation. In Bacillus sub...
Mevalonate pathway rewiring driven by enhancer remodelling confers resistance to KRAS inhibitors in colorectal cancer
Timed secreted proteomes reveal regulation of hepatokines by the liver circadian clock
Pre-treatment bacterial cell states shape antibiotic-induced transcriptional reprogramming and survival
High temperature Néel skyrmions in simple ferromagnets
Abstract A wide variety of chiral non-collinear spin textures have been discovered and have unique properties that make them highly interesting for technological applications. Howeve...
Dynamic cell fate transitions during morphallactic regeneration
Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum
Abstract Knee osteoarthritis affects 40% of people during their lifetime, significantly impacting societies worldwide. Its molecular pathogenesis remains poorly...