Mevalonate pathway rewiring driven by enhancer remodelling confers resistance to KRAS inhibitors in colorectal cancer

Y Yaoyu Guo Y Yi Zhong P Peishan Hu Y Yufeng Chen (Power Battery & Systems Research Center, State Key Laboratory of Catalysis) W Wenjun Guo J Jianfeng Chen P Peiyong Guan Z Zhengran Zhou F Fang Zhu (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry) X Xian Zeng (College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry) J Jiuping Gao Q Qiqing Xiong Z Zhaoliang Yu C Chuling Hu Z Zerong Cai (Department of Molecular and Cell Biology, University of California Berkeley) X Xiaoyu Xie (Department of Anesthesiology, West China Hospital, Sichuan University) J Jing Han Hong J Jason Yongsheng Chan W Wenyu Wang (Department of Pharmaceutics, School of Pharmacy) D Dechang Diao X Xiaojun Xia Q Qiang Yu C Choon Kiat Ong Y Yijun Gao (Key Laboratory of Biomedical Polymers Ministry of Education, College of Chemistry and Molecular Sciences) X Xiaojian Wu J Jing Tan