Nature Communications
Articles in this Issue
Brieflow: an integrated computational pipeline for high-throughput analysis of optical pooled screening data
Abstract Optical pooled screening (OPS) has emerged as a powerful technique for functional genomics, enabling researchers to link genetic perturbations with complex cellular morpholo...
Universal rhythmic architecture uncovers two modes of neural dynamics
Abstract Understanding the organizing principles of brain activity can advance neurotechnology and medical diagnosis. Traditionally, neural activity is viewed as consisting oscillati...
Non-decameric NLRP3 reveals a TGN/MTOC-distal pathway of inflammasome activation
Abstract The NLRP3 inflammasome contributes to a wide range of conditions from infections to Alzheimer’s disease. NLRP3 forms an inactive decameric cage, that up...
Improving protein and protein interactions using pseudo-dimers derived from monomeric proteins
Event-based spatiotemporal networks for modelling emergent phenomena in complex systems
Soft mode origin of charge ordering in superconducting kagome CsV3Sb5
Abstract Charge-density-wave (CDW) order and superconductivity coexist in the kagome metals AV 3 Sb 5...
The I gene defines a dynamic NLR cluster conferring broad potyvirus resistance in common bean
Abstract Common bean ( Phaseolus vulgaris ) is a major grain legume for human...
Inference of upstream-mutation and metabolomic-signature causality identifies prognostic biomarkers and therapeutic targets in pancreatic cancer
Single-phage profiling illuminates viral individuality during bacterial cell fate determination
Integration of donor microbiota following FMT correlates with anti-PD-1 response in melanoma
Mitochondrial RNA degradation regulates differentiation, stemness, and immune sensitivity in acute myeloid leukemia
CryoWriter: a robotic solution for improved Cryo-EM grid preparation
Abstract Cryo-electron microscopy (cryo-EM) structure determination relies on preparing thin, vitreous films of sample solution on EM grids. Cryo-EM is a mature technology, but prepa...
Supercurrent effect in a charge density wave intertwined superconductor
AMOC slowdown amplifies North Atlantic salinity variability to unprecedented levels
Piezomagnetoelectric effects in a candidate Kitaev magnet
Abstract The exactly solvable Kitaev model with its frustrated bond-dependent interactions has attracted enormous attention due to its exotic physics hosting fra...
Two Plasmodium vivax hypnozoite-expressed RNA-binding proteins inhibit liver stage replication
Abstract Plasmodium vivax (Pv) forms non-replicating liver stages called hypnozoites, which activate after primary infection, and cause relap...
Electrostatic bimodality of human cytosolic DNA sensor cGAS-dsDNA condensates revealed by millisecond flashing electrophoretic separation
OFC-induced network modularity improves positive symptoms and attentional alertness in schizophrenia: a combined rTMS-fMRI study
Abstract Repetitive Transcranial Magnetic Stimulation (rTMS) targeting the orbitofrontal cortex (OFC) has emerged as a promisingerapeutic option for drug-naïve people with schizophre...
Measurement of analogue Hawking radiation stimulated by a single photon
Children use algorithm induction to discover patterns in data
Abstract Humans are unique in our ability to acquire diverse skills and inhabit myriad environments, but the cognitive mechanisms underlying such fast, flexible learning remain unres...
Pan-cancer single-cell atlases of mouse and human tumor-associated dendritic cells
COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy
Abstract Primary mitochondrial diseases (PMDs) affect approximately 1 in 4300 individuals and cause early-onset neuromuscular and multisystem dysfunction with re...