Nature Communications
Articles in this Issue
Prodrug nanoplatform for triggering ferroptosis to eliminate senescent cells in age-associated pathologies
Sodium disrupts mitochondrial energy metabolism to execute NECSO
Accumulation of Trehalose 6-Phosphate in Candidozyma auris results in Decreased Echinocandin Resistance and Tolerance
Spatial fluorescence barcode by transiently luminescent DNA beads
Ethylene promotes branch formation but inhibits tendril development in cucumber
Structure of the 30S translation initiation complex coupled to paused RNA polymerase and its potential for riboregulation
Abstract In many bacterial species, transcription and translation can be coupled physically, with potential impact on the rates and efficiency of gene expression. Here, we present st...
Primary SARS-CoV-2 exposure by vaccination or infection shapes immune responses to omicron variants among a Spanish cohort
Abstract The comparison between vaccine-induced and infection-acquired adaptive immunity, and their co-occurrence —referred to as “hybrid immunity”— is of great interest and remains...
Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation
Abstract Dopaminergic signaling shapes large-scale brain network architecture, constraining neural communication along a principal gradient that spans unimodal sensorimotor to transm...
Human monoclonal antibodies that target clade 2.3.4.4b H5N1 hemagglutinin
Why covalent organic frameworks grow twisted on graphite
Wolbachia enhances ovarian development in the rice planthopper Laodelphax striatellus through elevated energy production
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity
Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock response
Abstract Cells must respond rapidly to heat stress by activating multiple signaling pathways that preserve proteostasis. In budding yeast, this includes induction of Hsf1 and Msn2/4-...
The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein
Abstract Short linear motifs (SLiMs) in disordered protein regions direct numerous protein–protein interactions, yet most remain uncharacterized. The Asn-Pro-Phe (NPF) motif is a wel...
Sequestration of the phagocyte metabolite itaconate by Pseudomonas aeruginosa RpoN promotes successful pulmonary infection
HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killing
Beyond phase boundaries: atomic mechanisms governing structure and property variations in (K, Na)NbO3-based ferroelectrics
Structural basis of double-stranded RNA recognition by the J2 monoclonal antibody
Abstract Double-stranded (ds) RNAs are major structural components of the transcriptome, hallmarks of viral infection, and primary triggers of innate immune responses. The J2 monoclo...
4D printing of trigger-free shape-memory hydrogels towards self-adaptive substrates for bioelectronics
Widespread land surface cooling from paddy rice cultivation revealed by global satellite mapping
Impact and cost-effectiveness of the community-led AMETHIST intervention among female sex workers in Zimbabwe
Abstract Female sex workers (FSW) face high HIV risk of HIV transmission and acquisition. The AMETHIST (“Adapted Microplanning: Eliminating Transmissible HIV In Sex Transactions”) tr...
Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data
Abstract Gene perturbation screens (e.g. CRISPR-Cas9) assess the impact of gene disruption on in-vitro cellular phenotypes (e.g., proliferation, anti-viral respo...
Environmental exposures associated with the gut microbiome and resistome of pregnant women and children in Northwest Ecuador
Abstract Inadequate water, sanitation, and hygiene (WASH) infrastructure may increase exposure to antimicrobial resistance (AMR). In addition, close human-animal...
De novo sequencing of glycans by ion mobility-mass spectrometry using a self-expanding database
Temperature variability projections remain uncertain after constraining them to best performing Large Ensembles of individual Climate Models
Abstract Changes in temperature variability affect the frequency and intensity of extreme events, as well as the regional range of temperatures that ecosystems and society need to ad...