Nature Communications
Articles in this Issue
Multi-layered transcriptional control of glycogen metabolism coordinates thermogenic remodeling of white adipocytes in male mice
Abstract Thermogenic activation of subcutaneous white adipocytes requires glycogen synthesis and turnover. Here we show that β-adrenergic stimulation induces a d...
Molecular insights into ago-allosteric modulation at cysteinyl leukotriene receptor 2
Abstract Cysteinyl leukotriene receptor CysLT2R, which is activated by the endogenous cysteinyl leukotrienes (CysLTs) LTC4, LTD4, and LTE4, has emerged as a pote...
Capturing coherent pseudorotation through conical intersection in photoionized benzene
Processing of natural scenes in the human pulvinar
Reconstruction and analysis of pore blockage fouling in ceramic ultrafiltration membranes through FIB-SEM
Expanded genetic alphabet increases structural and chemical diversity of six-letter DNA for high-affinity protein-targeting aptamers
Blue-light-enhanced interaction between ZmCRY1s and GL2 modulates epidermal wax composition in Zea mays
Genome-wide screen reveals dependence of break induced replication on several distinct checkpoints
Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1-/- plus mtDNA mutant mice
An unconventional pathway to correlate the octahedral tilt coupling and spin-orbit reconstruction at oxide interfaces
Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy
Abstract An active lifestyle protects against cardiovascular diseases, yet its mechanisms in modulating the cardiac immune environment and preserving cardiac fun...
Structural basis for genome-wide site-specific DNA recognition by Nuclear Factor IA
A synthetic cell phage cycle
Persistent pneumococcal colonisation in antiretroviral-treated HIV infection is associated with nasal inflammation
Chiroptical isomerization in chiral covalent organic frameworks with identical mesoscopic helicity
Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma
Abstract Neutrophils are vital innate immune cells shown to infiltrate glioblastomas, however we currently lack the molecular understanding of their functional states within the tumo...
PD-1/ PD-L1 bispecific antibody IBI318 combined with lenvatinib in advanced non-small cell lung cancer with acquired resistance to immune checkpoint inhibitors: a phase II trial
Structure and mechanism of the broad spectrum CRISPR-associated ring nuclease Crn4
Abstract Type III CRISPR systems detect the presence of RNA from mobile genetic elements (MGE) in prokaryotes, providing antiviral immunity. On activation, the catalytic Cas10 subuni...
70 km long-range Raman distributed optical fibre sensing through enhanced anti-distortion coding and waveform reconstruction
Abstract The practical implementation of Raman distributed optical fibre sensing has been fundamentally constrained by the inherent low signal-to-noise ratio (SNR), particularly for...
Saffold virus exploits integrin αvβ8 and sulfated glycosaminoglycans as cooperative attachment receptors for infection
Abstract Saffold virus (SAFV), a member of the species Cardiovirus saffoldi within the Picornaviridae...
Development of a replication-defective mpox virus platform for fundamental and therapeutic research
Spatial patterning of the epigenome during vertebrate gastrulation
Convergent causal mapping unravels distinct frontal networks for visuospatial selective attention
Abstract Orienting visuospatial attention towards relevant stimuli is vital for effective environmental interactions. Current attentional control models rely on functional neuroimagi...