Nature Communications
Articles in this Issue
Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis
Maintenance of intestinal CX3CR1+ macrophage homeostasis defines post-treatment control in SIV-infected macaques
Abstract Achieving durable viral remission without antiretroviral therapy (ART) remains a central challenge in HIV-1 cure research. Using a pathogenic SIV model...
DNA-PK-mediated phosphorylation of STAT6 establishes a non-canonical type 2 immunity axis to prevent macrophage senescence
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A
Abstract The intrinsically disordered MYC proteins are master regulators of cellular growth and function, but when deregulated they become cancer drivers. MYC-protein interactions ar...
Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice
Abstract An unhealthy diet disrupts feeding behavior and the gut microbiota, but whether early-life dietary effects persist, or can be restored later in life, re...
Cryo-EM structures of light chain fibrils from abdominal fat biopsies of multiple myeloma patients
Harnessing a germ‑free mouse gut bioreactor for directed evolution of probiotics to combat non-alcoholic fatty liver disease
A unified symmetry framework for spin–ferroelectric coupling in altermagnetic multiferroics
Nature-inspired solid-state proton diode membrane for high-performance force-electric conversion
Reconstruction of the lifeways of Central European Late Bronze Age communities using ancient DNA, isotope and osteoarchaeological analyses
Abstract The Late Bronze Age (ca. 1300–800 BCE) of Central Europe is often characterised as a period of increasing mobility, socioeconomic transformation, environmental fluctuations,...
Disordered light-harvesting aggregates can host functional vibronic couplings at room temperature
Chiral inheritance effect in the reactive cystine-based coassembly system
Synergistic nitrogen and endohedral MoCl5 doping for ultrahigh-conductivity carbon nanotube fibers
SFPQ directs histone H3.3 deposition to R-loops in DNA repeats to protect genome stability
Abstract R-loops are three-stranded nucleic acid structures composed of an RNA:DNA hybrid duplex and a displaced single-stranded DNA loop. Unscheduled or persistent R-loops drive gen...
Male obesity causes adipose mitochondrial dysfunction in F1 mouse progeny via a let-7-DICER axis
Switching speed limits in electrically driven VO2 structural Mott–Peierls transition
Abstract Mott materials are archetypal quantum systems actively explored as next-generation electronic and photonic platforms, with potential applications spanni...
Evaluating spatially targeted HIV interventions and harm reduction services among people who inject drugs in a high-burden setting
Trimbody with rigid AI-designed scaffolds enables atomic-resolution cryo-EM structure determination of small proteins
B7-H3-mediated cis-inhibition of EGFR by a tumor-selective bispecific antibody enhances anti-tumor efficacy and minimizes toxicities
Non-Markovian relaxation spectroscopy of fluxonium qubits
Abstract Recent studies have shown that parasitic two-level systems (TLS) in superconducting qubits, which are a leading source of decoherence, can have relaxati...
Combination of PARP and KRASG12D inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC
Comment on the article “Experimental confirmation of driving pressure boosting and smoothing for hybrid-drive inertial fusion at the 100-kJ laser facility”
Context-dependent translation inhibition as a cancer therapeutic modality
Clinically distinct metabotypes of pediatric MASLD identified through unsupervised clustering of NASH CRN data
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common liver disease worldwide, yet treatment remains “one size fits all,” despite phenotypic he...