Nature Communications
Articles in this Issue
Versatile and sensitive detection of mono- and poly(ADP-ribosyl)ation reveals XRCC1-dependent remodelling of PARP1 signalling
Abstract ADP-ribosylation has long been recognised as a key regulator of essential signalling pathways, including the DNA damage response. However, only recent and ongoing technologi...
An ultrathin ionic thermoelectric cell design utilizing near body heat for self-powered wearable electronics
Wastewater surveillance reveals patterns of antibiotic resistance across the United States
Abstract Antibiotic resistance is a growing public health threat, with over 2.8 million antibiotic-resistant infections and 35,000 attributable deaths annually i...
Mitochondrial vulnerability underlies myocarditis from COVID-19 mRNA vaccine
High-quality perovskite crystal for efficient and bright pure-blue light-emitting diodes with narrow emission
Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model
Whole-proteome phage immunoprecipitation sequencing reveals germ cell tumor–specific immunosignature
MIC-Drop-seq: scalable single-cell phenotyping of mutant vertebrate embryos
Tim-3 agonist restrains ILC2 function and attenuates airway hyperreactivity via NLK pathway
Genetic architecture of sleep in a genome wide association study of device measured sleep traits
Abstract Sleep is essential for health and regulated by genetic and environmental factors. We perform genome-wide association studies of device-measured sleep du...
Deep-branching Chloroflexota lineages illuminate the eco-evolutionary foundation of cross-ecosystem colonization
Abstract Bacteria span Earth’s ecosystems, coupling ecological versatility with genome-architectural reconfiguration across shifting physicochemical conditions. Yet the genomic route...
Manifold topological deep learning for biomedical data
Global hotspots of particulate organic carbon losses under climate change
Architecture and regulation of nanoscale chromatin domains
Abstract Nanoscale chromatin domains have emerged as fundamental units of mammalian genome organization during interphase and mitosis. Single-molecule localization microscopy now ena...
An end-to-end generalizable deep learning framework to comprehensively analyze transcriptional regulation
TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade
Dawn-dusk Asymmetrical Distribution of Saturn’s Cusp
Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3
Topological non-Abelian gauge structures in Cayley-Schreier lattices
Path entropy-driven design of solid-state electrolytes
Abstract The development of high-performance solid-state electrolytes (SSEs) has entered a critical stage, where entropy-driven strategies offer transformative p...
YY1/Asprosin/PFKP axis regulates glycolytic metabolic and exacerbates pathological cardiac hypertrophy
Spontaneous crack healing in calcite reveals the influence of dynamic strain evolution and surface chemistry
Abstract The mechanics of fracture healing in calcite remain poorly constrained yet are fundamental to managing fluid transport in geothermal reservoirs and hydrocarbon systems. Here...
Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance
Abstract New antimalarial drugs are needed to combat the current emergence and spread of Plasmodium falciparum parasite r...
The origins of patchy aurora at Jupiter
NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction
Abstract Ischemic heart failure remains a major clinical challenge, underscoring the need to better understand post-infarction immune mechanisms and identify new therapeutic targets....