Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation

S Satoshi N. Omura R Ryoya Nakagawa S Shohei Kajimoto S Sae Okazaki S Soh Ishiguro H Hideto Mori K Kosuke Onishi Y Yuji Kashiwakura T Takafumi Hiramoto K Kio Horinaka M Mamoru Tanaka H Hisato Hirano K Kasey Jividen K Keitaro Yamashita S Shengdar Q. Tsai N Nozomu Yachie T Tsukasa Ohmori H Hiroshi Nishimasu O Osamu Nureki