Nature Communications
Articles in this Issue
Dynamic recruitment of CaMKII into SHANK3 phase-separated condensates tunes postsynaptic density remodeling during long-term potentiation
Experimental demonstration of high space compression by optical spaceplates
Abstract The large physical size of optical imaging systems is one of the greatest constraints on their use, limiting the performance and deployment of a range o...
Dissolved organic matter-generated photoelectrons enable microbial antimonate reduction in mine stream sediments
Abstract Antimony contamination in mining-impacted river basins poses persistent environmental risks, yet the microbial processes governing antimony redox transf...
Author Correction: Emergent patterns of patchiness differ between physical and planktonic properties in the ocean
Identification of hot spring Obelisk-like RNA replicons and expanded diversity of the Obelisk superfamily
Abstract Recent extensive metatranscriptome mining vastly expanded the range of apparently covalently closed circular (ccc) RNA replicons. A notable family of such replicons is Obeli...
Near-unity charge transfer efficiency on bare semiconductor photoanodes induced by polyols and ammonia co-oxidation
Photoactivatable CRISPR/Cas13d via upconversion nanoparticles for deep tissue RNA engineering and orthopedic therapy
Abstract Spatiotemporal control of RNA therapeutics remains a fundamental challenge limiting clinical translation. Here, we develop a photoactivatable CRISPR/Cas13d (paCas13d) system...
A high-resolution spatial map of cilia-associated proteins in the human fallopian tube
Abstract Molecular alterations in the fallopian tubes play a pivotal role in the development of cancer and reproductive disorders, yet their molecular landscape at the protein level...
Assembly of two functionally-distinct protein import complexes in the outer membrane of plant chloroplasts
Abstract The TOC translocon delivers thousands of nucleus-encoded proteins to chloroplasts and related non-photosynthetic plastids. It comprises the β-barrel cha...
SPNS2 exports sphingosine-1-phosphate and imports glucose
Polymer-templated mesoscale assembly directs synthesis of centimetre-scale perovskite single crystals
Structure-informed deep generation enables de novo metabolite annotation in untargeted metabolomics
Engineered BCG selectively triggers trained immunity in tumor-associated macrophages and sensitizes glioblastoma to radiotherapy in mice
Detecting complex-energy braiding topology in a dissipative atomic simulator with transformer-based geometric tomography
Dramatic increase in ecosystem respiration causes record-breaking atmospheric CO2 growth rate in 2024
Phage homing endonuclease amplifies anti-defense genes to evade bacterial immunity
Abstract Bacteriophages must overcome diverse bacterial immune systems, yet the molecular principles enabling such escape remain poorly understood. Here, we show...
Hotspot pocket-based discovery of urea transporter selective inhibitors
Abstract Urea transporter (UT) inhibitors are a promising class of diuretics, as selective inhibitors targeting UT-A subtypes have demonstrated considerable therapeutic potential. He...
Generative approaches to kinetic parameter inference in metabolic networks via latent space exploration
Abstract Dynamic (kinetic) models track time-varying metabolite concentrations, fluxes, and enzyme levels, quantifying responses to genetic and environmental per...
Recurrent DNA break clusters drive replication-stress-induced copy number variants and genome diversification
Abstract Copy number variants (CNVs) are strongly implicated in neurological and psychiatric disorders and brain cancer, yet the process by which replication stress generates CNVs—an...
Author Correction: Large emissions of CO2 and CH4 due to active-layer warming in Arctic tundra
Exploratory analyses of clinical trials - what can they tell us and what are the potential pitfalls?
Predicting and achieving self-recoverable mechanoluminescence based on contact electrification
Elucidating the Facet-Dependent Oxygen Reduction Reaction Performance of Cu Nanosheet over N-O co-Doped Graphene
Ozone mitigates extended growing season and enhanced vegetation greenness driven by environmental change
Abstract Rising temperature and elevated CO 2 concentrations lead to extended growing seasons and enhanced vegetation gre...
Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking
Abstract Secreted proteins regulate many aspects of animal biology and are attractive targets for biomarkers and therapeutics. However, comprehensively identifyi...