Engineered BCG selectively triggers trained immunity in tumor-associated macrophages and sensitizes glioblastoma to radiotherapy in mice

K Ke Ren Z Ziyang Yuan L Lei Lei (Department of Molecular, Cell and Developmental Biology, University of California) Z Ziyuan Xiao (Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University) N Ningyi Ma (Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University) G Guodong Wang (Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences) N Ningyi Sun (Department of Clinical Microbiology, School of Laboratory Medicine, Chengdu Medical College) T Tai Yang Z Zhiyong Chang L Liang Qin Y Ying Xu D Dahai Yu L Lizhou Jia H Haishi Qiao (Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University)

Article Details

Volume / Issue Vol. 17, Issue 1
Published April 20, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (14)

K

Ke Ren

Z

Ziyang Yuan

L

Lei Lei

Department of Molecular, Cell and Developmental Biology, University of California

Z

Ziyuan Xiao

Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University

N

Ningyi Ma

Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University

G

Guodong Wang

Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences

N

Ningyi Sun

Department of Clinical Microbiology, School of Laboratory Medicine, Chengdu Medical College

T

Tai Yang

Z

Zhiyong Chang

L

Liang Qin

Y

Ying Xu

D

Dahai Yu

L

Lizhou Jia

H

Haishi Qiao

Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University