Nature Communications
Articles in this Issue
Collagen hybridizing peptide imaging and delivery of therapeutic antibody in rheumatoid arthritis models
Abstract The use of immunosuppressive therapies for rheumatoid arthritis (RA) is associated with substantial adverse effects. In addition, existing diagnostic reagents are limited in...
TENT5C extends Odf1 poly(A) tail to sustain sperm morphogenesis and fertility
Abstract Changes in the poly(A) tail length of Odf1 and other transcripts critical for male fertility have been linked to...
Disruption of the SAGA CORE triggers collateral degradation of KAT2A
Abstract The Spt-Ada-Gcn5 acetyltransferase (SAGA) complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase (HAT), KAT2A...
Improved dynamic MRI of the wrist and heart at 0.55 T enabled by rapid 3D printed flexible coils
Vertically stacked immobilized photocatalyst devices towards land-efficient solar hydrogen production
Annually resolved atmospheric CO2 growth rate over the past nine centuries
Structural basis of QueC-family protein function in qatABCD anti-phage defense
Abstract QueC proteins are nucleoside biosynthesis enzymes required for production of the 7-deazaguanine derivative queuosine. Recently, QueC-family proteins wer...
Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC
Abstract Three-dimensional nuclear DNA architecture comprises well-studied intra-chromosomal ( cis ) folding and less cha...
Highly disordered nanoporous carbons for enhanced energy storage in supercapacitors
Abstract There has been a lack of clear principles for designing nanoporous carbons with enhanced performance in supercapacitors due to their structural complexity. Our recent NMR an...
Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids
Abstract Leigh syndrome (Leigh) is an untreatable mitochondrial disorder characterized by lactic acidosis and basal ganglia and midbrain pathology, leading to ps...
Igh nuclear speckle association promotes V(D)J recombination
Oceanic fronts shape hemispheric contrasts in polar stratospheric extremes
Abstract Sudden Stratospheric Warmings (SSWs) and Polar Stratospheric Clouds (PSCs) exhibit striking inter-hemispheric asymmetries: SSWs are frequent in the Arctic but rare in the An...
Author Correction: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Efficacy and safety of albumin combined with endovascular therapy in the treatment of patients with acute ischemic stroke: a randomized clinical trial
Comprehensive assessment of transcriptome assembly quality using CATS
Abstract Accurate assessment of transcriptome assembly quality is critical to ensure the reliability of subsequent transcriptomic analyses. Here, we present CATS (Comprehensive Asses...
Janus structure breaks the solar incidence angular constraint insu photothermal anti-icing
Co-deposited inverted perovskite photovoltaics towards 27% efficiency via vertical redistribution of self-assembled-molecules and in-situ crosslinking
Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging
Abstract Obesity impairs subcutaneous adipose tissue function, which predisposes to chronic cardiometabolic comorbidities and accelerated biological aging. Howev...
DNA deformability in sequence-dependent capture of E. coli gyrase
Cation-tuned acidic electrified interface for hydrogen peroxide electrosynthesis with industrial-level current densities in natural seawater
Abstract Electrocatalytic oxygen reduction reaction in seawater represents a sustainable approach for hydrogen peroxide (H 2...
Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation
Fast-kinetic multivalent ion storage enabled by multiscale structural modulation in two-dimensional magnetic materials
Molecular and physiological acclimation to low light and iron scarcity in a globally abundant oceanic pelagophyte
Abstract Pelagomonas calceolata is a widely distributed marine alga and is among the most numerous eukaryotes on Earth. It is abundant in sub...
Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics
Salicylic acid modulates its catabolic enzymes via proteasomal degradation linked to SCF-associated proximity networks
Abstract Salicylic acid (SA) is a central regulator of plant immunity, and precise control of its levels is essential to balance defense and growth. However, the...