Nature Communications

Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation

S Stephen QR Wong K Kazukuni Hayashi E Ethan J. Subel Y Yung Hsing Huang H Hongbo Gao H Haley E. Garcia S Sophie J. Porter M Mustafa Karabicici X Xen Ping Hoi M Mark D. Alonzo A Armine Kasabyan E Efrosini Tsouko C Crystal S. Shin L Lisa Bouchier-Hayes D Dimitrios Korentzelos C Chen Chen M Michael Brooks Z Zheng Yin R Renil S. Titus L Lan Zhou (Engineering Research Center of Organosilicon Compounds and Materials (Ministry of Education), Hubei Key Lab on Organic and Polymeric OptoElectronic Materials, College of Chemistry and Molecular Sciences, The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, and State Key Laboratory of Metabolism and Regulation in Complex Organisms) Y Yinan Gong (Department of Immunology) Y Yulin Li (Division of Life Science, Hong Kong University of Science and Technology) S Stephen TC Wong Z Ziad El-zaatari D Dharam Kaushik R Raj Satkunasivam F Fotis Nikolos K Keith S. Chan
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Article Details

Volume / Issue Vol. 17, Issue 1
Published April 20, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio
ISSN: 2041-1723 Open Access Life Sciences

Authors (28)

S

Stephen QR Wong

K

Kazukuni Hayashi

E

Ethan J. Subel

Y

Yung Hsing Huang

H

Hongbo Gao

H

Haley E. Garcia

S

Sophie J. Porter

M

Mustafa Karabicici

X

Xen Ping Hoi

M

Mark D. Alonzo

A

Armine Kasabyan

E

Efrosini Tsouko

C

Crystal S. Shin

L

Lisa Bouchier-Hayes

D

Dimitrios Korentzelos

C

Chen Chen

M

Michael Brooks

Z

Zheng Yin

R

Renil S. Titus

L

Lan Zhou

Engineering Research Center of Organosilicon Compounds and Materials (Ministry of Education), Hubei Key Lab on Organic and Polymeric OptoElectronic Materials, College of Chemistry and Molecular Sciences, The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, and State Key Laboratory of Metabolism and Regulation in Complex Organisms

Y

Yinan Gong

Department of Immunology

Y

Yulin Li

Division of Life Science, Hong Kong University of Science and Technology

S

Stephen TC Wong

Z

Ziad El-zaatari

D

Dharam Kaushik

R

Raj Satkunasivam

F

Fotis Nikolos

K

Keith S. Chan

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