Nature Communications
Articles in this Issue
A metabolite-bridged complex between SerRS and SIRT2 couples NAD⁺ metabolism to translation control
Abstract Cellular homeostasis requires tight coordination between metabolic and translational networks. Here we identify a direct molecular link between these processes through a cry...
Assessing hypochlorite selectivity of corrosion resistance catalysts for alkaline seawater splitting
Abstract Using seawater for hydrogen production via electrolysis is increasingly attractive for cost savings. The main challenge is the competition at the anode between hydroxide oxi...
Hierarchical optimization predicts plasticity in the macaque inferior temporal cortex following object training
Abstract How does the primate brain coordinate plasticity when learning to discriminate new objects? We measured consequences of object learning on inferior temporal (IT) cortex, a k...
Body surface potential mapping of the cortico-muscular axis using smart textile electrode arrays
Abstract Cutaneous electrophysiology is a fundamental non-invasive technique for assessing electrically active organs such as the brain, heart, and muscles. Standard approaches, howe...
High-performance stretchable conductive film on complex microscale structures via spontaneous fusion of liquid metal
Sensitive infrared photodetection enabled by in-sensor background-offset cancellation in a mixed-dimensional van der Waals heterostructure
Particle-associated diazotrophs drive nitrogen fixation in Arctic subsurface waters of the Barents Sea
Abstract Biological dinitrogen (N 2 ) fixation sustains productivity in oligotrophic oceans and is now also thought to co...
Pulmonary mRNA-LNP vaccines for rapid and durable protection against bacterial infection
Unveiling the landscape of Mottness and its proximity to superconductivity in 4Hb-TaS2
Urbanization processes widen global divergence in extreme temperature variability
Abstract Extreme temperature variability (ETV) is a key dimension of climate risk for billions of residents. However, how urbanization shapes global ETV divergence remains unclear. H...
Neuronal dynamics, timing, and flow of sensory and choice-related information in auditory-prefrontal circuitry
Selenium atom transfer enables selective bridged alkene-arylamine cycloaddition
Cellular heterogeneity of hepatic granuloma formation and evolution in murine schistosomiasis japonica
Abstract Schistosomiasis morbidity and mortality are primarily driven by egg-triggered granulomas with subsequent fibrosis. However, the dynamics of cellular com...
Dynamic immune profiling predicts response to radiation plus anti-PD-1 therapy in oligometastatic renal cell carcinoma
Spatial transcriptomic profiling of ovarian clear cell carcinoma reveals heterogeneity in OXPHOS and EMT gradients
Structural basis of lipid-dependent allosteric gating mechanisms for PC1-PC2 ion channel
Immune protection and persistence in Pseudomonas aeruginosa infections by pyruvate cross-feeding
Spliceosomal proteins direct RNA methylation to modulate gene expression and silence retrotransposons
Abstract RNA modifications are fundamental to gene regulation and RNA processing, yet their diversity and transcript specificity remain incompletely defined. Her...
Embodied behavioural complexity in a ciliated microorganism
Abstract Most animals coordinate behaviour using neural computations. Yet, single-celled organisms also exhibit stimulus-responsive, even cognitive, actions. To understand how a sing...
Loss of the USP22 deubiquitylase confers resistance to chemotherapy in small cell lung cancer
Abstract Small cell lung cancer (SCLC) responds exceptionally well to cytotoxic chemotherapy. However, relapse with the emergence of chemoresistant disease is ra...
Structural dynamics of RNA polymerase II throughout the nucleotide addition cycle
Abstract RNA polymerase II (RNAPII) drives gene expression through iterative nucleotide addition cycles (NACs) comprising translocation, substrate binding, and c...
Linoleic acid accelerates osteoarthritis progression in male rats by targeting iron-sulfur clusters to drive ferroptosis in chondrocytes
Systems-level analysis predicts no autotrophy-linked protein-RNA interactions in Clostridium autoethanogenum
Abstract Burning fossil fuels drives climate change with detrimental consequences on humankind while waste accumulation from increasing consumption threatens bio...
Non-equilibrium correlated electron dynamics in triangular molecular assemblies
Abstract Understanding and controlling charge states at the level of individual electrons in molecular assemblies is often hindered by system complexity and the lack of reliable theo...
Dynamic control of laser driven electron acceleration in a photonic structure using programmable optical pulses
Abstract Progress in optical techniques has made precision control of the phase profile in optical pulses common and accessible in scientific laboratories. Carefully shaping the fiel...