Journal of Clinical Oncology
Articles in this Issue
Barriers and facilitators of adoption and implementation of a financial navigation program in Nigeria: An analysis of participant data from the COST-FIN trial.
TPS11187 Background: Financial toxicity is a critical issue in modern healthcare. The impact of financial toxicity is particularly pronounced in low- and...
Clinical and immunopathological evaluation and its comparison with consensus molecular subtypes of colorectal cancer.
3594 Background: This study aims to elucidate the prognostic impact of the immunoscore within the context of consensus molecular subtypes (CMS), tumor bud...
Real-world data vs pivotal trial outcomes of imatinib in newly diagnosed chronic myeloid leukemia patients.
e18565 Background: Chronic myeloid leukemia (CML) is driven by the BCR::ABL1 fusion gene, resulting in uncontrolled tyrosine kinase activity. The introduc...
Institutional experience with pancreatic head versus body/tail cancer: A comparison of treatment outcomes.
e16436 Background: Pancreatic ductal adenocarcinoma (PDAC) continues to rise globally, with a poor prognosis and devastating outcomes. This study aims to...
Exploring the role of posthumous organ donation attitudes: A comparative study of Egyptian cancer patients and healthy individuals.
e22605 Background: Organ transplantation is a critical intervention for patients with end-stage organ failure, including those suffering from cancer-relat...
Plasma proteome molecular sequencing–based prognostic nomogram in metastatic castrate-resistant prostate cancer (mCRPC).
e17057 Background: Currently non-specific protein factors (Alkaline Phosphatase-ALK, LDH, albumin) are used for identifying prognostic risk groups in mCRP...
Obesity-related cancer mortality in the US (1999–2020): A CDC WONDER analysis.
e23052 Background: Obesity is a major public health issue and a key risk factor for various cancers. This study examines U.S. mortality trends (1999–2020)...
Immune checkpoint inhibition in EBV-associated gastric cancer: A multi-center international retrospective analysis.
4043 Background: Epstein-Barr virus associated gastric cancer (EBVaGC) is found in ~9% of GC and is associated with a uniq...
Obesity paradox in non-small cell lung cancer (NSCLC) patients on immune checkpoint inhibitors: Real-world evidence using the global collaborative network database.
e20624 Background: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for about 85% of all cases. Immune checkpoint inh...
Advancing pain and symptom management in cancer: A data-driven analysis of care delivery, psychosocial support, and communication strategies.
e13588 Background: Effective pain and symptom management is critical in cancer care, yet gaps exist in addressing psychosocial needs and communication str...
Conducting stoma-free intersphincteric resection for ultra-low rectal cancers by selective delayed coloanal anastomosis, a single center experience.
e15622 Background: Intersphincteric resection (ISR) is aimed at preserving the anus in patients with ultra-low rectal cancers (uLRCs). Previous reports sh...
Efficacy and safety of envafolimab plus carboplatin and etoposide as first-line treatment for extensive-stage small-cell lung cancer: A prospective, single-arm, phase II trial.
8090 Background: Extensive-stage small cell lung cancer (ES-SCLC) is related to high malignancy and the poor prognosis. At present, immunotherapy combined...
Phase 2 cohort-2 trial in progress: Vabametkib plus lazertinib for patients with EGFR-mutant NSCLC who developed resistance to 1st-line, 3rd-gen-EGFR TKIs via C-Met dysregulation.
TPS8662 Background: Third-generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors (EGFR TKIs) have emerged as a promising first-line treatm...
Association between perceived interpersonal support and quality of life among adult patients with cancer undergoing chemotherapy at an academic cancer institute.
e23181 Background: The National Cancer Institute (NCI) defines quality of life (QOL) as “overall enjoyment of life.” Increasingly, cancer care is focused...
Molecular testing in primary advanced or recurrent endometrial cancer: A cost-effectiveness analysis.
5598 Background: The Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE) algorithm is a classification scheme for endometrial cancer (EC)...
Pre-existing cancer as a risk factor for poor outcomes after burn injury.
e24033 Background: With a growing population of cancer survivors, assessing health outcomes and improving patient care is increasingly important. Severe b...
Longitudinal ctDNA monitoring and prediction of anti-EGFR rechallenge outcomes in RAS/BRAF wild-type metastatic colorectal cancer (mCRC): The REMARRY & PURSUIT trials.
3514 Background: Anti‐EGFR monoclonal antibody (mAb) rechallenge involves re‐administering EGFR blockade after a treatment‐free interval to exploit clonal...
Effect of chatbot utilization on genetic testing uptake in diverse clinic settings.
e13710 Background: Chatbots are a digital health tool used to identify patients who may benefit from genetic testing, provide pre-test educational content...
Virtual reality for pain and anxiety management during bone marrow biopsy: A systematic review.
12075 Background: Bone marrow biopsy (BMB) procedures often cause significant pain and anxiety. Virtual reality (VR) has emerged as a promising non-pharma...
From data to dollars: Evaluating the predictive power of enhancing oncology model risk adjusters.
e13894 Background: The Enhancing Oncology Model (EOM) is an oncology-specific, total cost of care, value-based payment model. Performance in the model is...
Evaluation of prediabetes as a potential risk factor for breast cancer: A systematic review and meta-analysis.
e13168 Background: Recent research has shown conflicting results regarding the relationship between prediabetes and breast cancer. Factors such as insulin...
Prediction of extracapsular extension and seminal vesicle invasion in prostate cancer using preoperative MRI images combined with deep learning algorithms.
e17139 Background: Extracapsular extension (ECE) and seminal vesicle invasion (SVI) are critical factors in determining nerve-sparing decisions during rad...
Feasibility of Pap-derived ctDNA for detection of sporadic and Lynch-associated endometrial cancer.
10503 Background: Patients (pts) with Lynch Syndrome (LS) have high risk of endometrial cancer (EC) and are recommended risk-reducing hysterectomy (RR-Hys...
Economic and clinical impact of influenza virus infection in hospitalized lung cancer patients: A National Inpatient Sample analysis.
e20086 Background: Lung cancer is a leading cause of cancer-related mortality, with patients often susceptible to complications from infections, including...
Evaluating the impact of long-term glucocorticoid use on cancer risk in patients with rheumatologic diseases: A retrospective cohort study.
10532 Background: Long-term glucocorticoid (GC) therapy is widely used in the management of rheumatologic diseases, but its immunosuppressive effects have...