Journal of Clinical Oncology
Articles in this Issue
Postoperative re-profiling for identification of missed drivers and a high-risk fusion subgroup in non-pCR lung adenocarcinoma after neoadjuvant immunotherapy: A multicenter retrospective study.
8064 Background: For stage II-III driver-negative non–small cell lung cancer (NSCLC), neoadjuvant chemoimmunotherapy follo...
Real-world survival outcomes of radiotherapy-based treatment strategies for esophageal cancer: A population-based analysis from the Hong Kong CADRS.
e16122 Background: Radiotherapy is an essential component of treatment for esophageal cancer across definitive, perioperat...
Risk stratification and age-related disparities with abemaciclib responses in early ER-positive/HER2-negative breast cancer.
e12527 Background: Adjuvant abemaciclib improves outcomes in high-risk hormone receptor–positive, HER2-negative early brea...
Phase 2 data from ROSETTA Lung-02, a global randomized phase 2/3 trial of pumitamig (PD-L1 × VEGF-A bsAb) + chemotherapy in 1L NSCLC.
8513 Background: Pumitamig (BNT327/BMS986545) is an investigational PD-L1 × VEGF-A bsAb designed to restore effector T-cel...
Cancer recognition and assessment through non-invasive evaluation (CRANE): A prospective clinical validation study of a multi-biomarker class multi-cancer early detection (MCED) test in Japan.
TPS10629 Background: Japan has established screening programs for gastric, colorectal, lung, cervical, and breast cancers....
Arrhythmic outcomes following immune checkpoint inhibitor (ICI) therapy in patients with non–small cell lung cancer (NSCLC) without heart failure or myocarditis.
e24006 Background: Despite the established prognostic benefit, immune checkpoint inhibitors (ICIs) are associated with imm...
Efficacy of neoadjuvant immunochemotherapy followed by surgery in locally advanced buccal squamous cell carcinoma: A single-center real-world study.
6081 Background: The 5-year overall survival (OS) rate for locally advanced (stage III–IV) buccal squamous cell carcinoma...
Standard-dose ripretinib plus sunitinib versus ripretinib dose escalation in advanced GIST after progression on four prior therapies: Preliminary results of a multicenter cohort study.
11534 Background: Patients with advanced GIST who progress after four lines of therapy, including imatinib, sunitinib, reg...
More than pain relief: Associations between provider compassion, anxiety, and burnout in ED oncology care.
12078 Background: Compassionate care is a cornerstone of high-quality oncology practice, especially in high-stress environ...
Rural-urban disparities in musculoskeletal functional limitation among cancer patients in the United States.
e13799 Background: As cancer survivorship increases, long-term physical function has emerged as a critical determinant of...
Ischemic heart disease as a competing cause of death among patients with lung cancer in the United States: A multiple cause-of-death analysis, 1999–2023.
11163 Background: Despite improvement in lung cancer prevention, early diagnosis & management, Ischemic heart disease...
Maintenance therapy after induction chemotherapy with anti-EGFR–antibody and survival in metastatic colorectal cancer: A retrospective real-world study.
e15613 Background: Maintenance therapy (MT) after induction chemotherapy in metastatic colorectal cancer remains clinicall...
Sequencing antibody-based and CAR-T therapies in relapsed/refractory follicular lymphoma: An anchored indirect comparison and parallel meta-analysis.
e19053 Background: Therapeutic options for relapsed/refractory (R/R) follicular lymphoma (FL) now include dual-targeted CD...
Incidence and prognostic impact of recurrence in esophageal carcinoma patients achieving complete pathological response after neoadjuvant chemoradiotherapy or perioperative chemotherapy.
4069 Background: Esophageal carcinoma remains a global challenge, ranking 7th in cancer-related mortality. While the CROSS...
Landscape of actionable genomic alterations in primary versus metastatic lesions from Chinese lung adenocarcinoma patients.
e20055 Background: Precision therapy improves outcomes in lung adenocarcinoma (LUAD) but requires accurate detection of ac...
Patterns of high-risk HPV positivity in Janakpur, Nepal: Implications for scalable cervical cancer screening.
e13632 Background: Cervical cancer prevention in Nepal is constrained by the absence of a national HPV vaccination program...
From relative risk to lives lost: Meta-analysis–based projection of invasive fungal infection burden attributable to systemic corticosteroids.
e18624 Background: Invasive fungal infections (IFIs) are a major cause of morbidity and mortality in patients with hematol...
Integrating multi-cancer early detection into cancer screening programs in the United States: A cost-effectiveness modeling study.
10523 Background: In 2021, standard-of-care (SoC) screening for breast, cervical, colorectal, lung, and prostate cancers i...
Telehealth use and end-of-life care outcomes among Medicare decedents with cancers.
11012 Background: Telehealth has become an increasingly important care modality following the COVID-19 pandemic. For patie...
Clinical outcomes with low-dose lorlatinib in <i>ALK</i> mutation–positive metastatic lung adenocarcinoma: Experience from a tertiary care center in a developing country.
e20764 Background: Lorlatinib is a highly effective third-generation ALK inhibitor, with a 5-year progression-free surviva...
A cost-effectiveness analysis of JAK inhibitor therapy versus allogeneic stem cell transplantation in myelofibrosis.
e18606 Background: Optimal management of myelofibrosis (MF) requires balancing the long-term overall survival benefits of...
Non-Hodgkin lymphoma and diabetes-related mortality in the United States, 1999-2023: A CDC WONDER analysis.
e19091 Background: Individuals with diabetes mellitus and non-Hodgkin lymphoma (NHL) experience substantially higher morbi...
Early corticosteroid dosing after anti-CD19 CAR-T therapy for large B-cell lymphoma: Multicenter associations with neurotoxicity, cytokine release syndrome, and survival.
7020 Background: Corticosteroids are key to CAR-T toxicity management, but the impact of early dosing remains unclear. Ove...
Patient characteristics and nutrition interventions among referrals to outpatient registered dietitians in a tertiary cancer center: Retrospective analysis.
e13587 Background: Malnutrition in cancer patients is linked to diminished functional capacity, greater treatment toxicity...
Geographic and rural–urban patterns in pediatric and AYA malignant brain tumor mortality in the United States: A CDC WONDER analysis.
e14101 Background: Pediatric and adolescent/young adult (AYA) malignant brain tumors remain a leading cause of cancer-rela...