Journal of Clinical Oncology
Articles in this Issue
Concordance of <i>EGFR</i> and <i>KRAS</i> mutation status between primary non–small cell lung cancer and corresponding metastases: A systematic review and meta-analysis.
e20563 Background: Accurate molecular profiling is critical for NSCLC treatment selection. Metastatic tissue is frequently...
Longitudinal associations between patient and caregiver quality of life following hematopoietic stem cell transplantation.
12087 Background: Caregivers of patients undergoing hematopoietic stem cell transplantation (HSCT) experience high rates o...
Comparative safety and efficacy of obinutuzumab versus rituximab in combination with chemotherapy for follicular lymphoma: A systematic review and meta-analysis.
7068 Background: Follicular lymphoma is one of the most common non-Hodgkin lymphoma subtypes, typically presenting with ad...
Phase I/II study of LB1410, a bivalent TIM-3/PD-1 bispecific antibody, in combination with LB4330, a long-acting IL-10, in patients with advanced solid tumors.
2626 Background: LB1410 is an anti-PD-1/TIM-3 bispecific antibody (BsAb) developed by L&L Bio Co., Ltd., Shanghai, Chi...
A phase Ib, open-label, clinical trial of JAB21822 combined with second-line chemotherapy for metastatic colorectal cancer with <i>KRAS</i> G12C mutation.
3544 Background: Glecirasib (JAB-21822), a novel, covalent, small molecule KRAS G12C-GDP covalent inhibitor, has been show...
Predictivity of coagulation markers in diagnosing acute promyelocytic leukemia.
e18544 Background: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) characterized...
Making telehealth delivery of cancer care at home effective and safe: A pragmatic cluster randomized trial.
TPS1680 Background: Telehealth (TH) use for cancer care has rapidly expanded, both during and following the COVID-19 pande...
Distinct multi-omic signatures that underlie <i>KRAS</i> variants and survival in <i>KRAS</i> G12R pancreatic cancer.
4234 Background: KRAS mutations are the dominant oncogenic drivers of pancreatic ductal adenocarcinoma (PDAC). While KRAS...
Timing and prognostic impact of thromboembolic events in lung cancer patients treated with immune checkpoint inhibitors: A time-dependent real-world analysis.
11124 Background: Thromboembolic events (TEEs) are complications associated with malignancy, and emerging evidence suggest...
Age-stratified outcomes and racial disparities in hospitalized patients with endometrial cancer: A national analysis.
e17648 Background: The incidence of endometrial cancer is increasing in both younger and older populations, yet national a...
Impact of recent chemotherapy exposure on overall survival in patients with diffuse large B-cell lymphoma receiving bispecific antibody therapy.
e19093 Background: Diffuse large B-cell lymphoma (DLBCL) is cured with first-line chemoimmunotherapy, yet nearly 40% of pa...
CONVERGE-01 part 3: Ac-225 rosopatamab tetraxetan (CONV01-α) in Lu-PSMA-pretreated metastatic castration-resistant prostate cancer (mCRPC).
5011 Background: Ac-225 rosopatamab tetraxetan (CONV01-α, Convergent Therapeutics, Cambridge, MA), an alpha-emitting radio...
Fatal infection–associated adverse events with B-cell maturation antigen–directed therapies in multiple myeloma: A FAERS pharmacovigilance study.
e19552 Background: B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapies and bispecif...
Variations in postoperative patient-reported outcomes (PROs) attributed to patients, surgeons, or surgical centers.
e23277 Background: Postoperative PROs reflect patients’ subjective experiences and are influenced by numerous factors, inc...
Phase 1 first-in-human trial of AG01, a recombinant humanized monoclonal antibody to progranulin/glycoprotein 88 (GP88) to determine the safety, tolerability, pharmacokinetics, and preliminary antitumor activity in subjects with advanced solid tumor malignancies.
TPS2669 Background: Progranulin also called GP88/PGRN plays a major role as an autocrine growth & survival factor asso...
Genetic testing in endometrial cancer (GenEC): A study on the patient experience with MSK-IMPACT.
e22635 Background: Guidelines recommend consideration of genetic testing (GT) for patients with endometrial cancer (EC); h...
Differences in the receipt of recommended cardiovascular assessment among cancer survivors in the United States by atherosclerotic cardiovascular disease status.
12027 Background: Cardio-oncology guidelines recommend annual cardiovascular (CV) assessment among cancer survivors, parti...
Patterns of prostate-specific antigen levels for early detection of prostate cancer in sub-Saharan Africa.
e22501 Background: Prostate cancer remains a major cause of morbidity and mortality among men in sub-Saharan Africa, large...
Spatial multi-omics profiling of the primary lung microenvironment to elucidate the mechanism of osseous metastasis in advanced NSCLC through imaging mass cytometry.
e20546 Background: Non-small cell lung cancer (NSCLC) is one of the world's deadliest cancers, including lung adenocarcino...
Examining the impact of community, knowledge, and shared support on the <i>EGFR</i> -mutated lung cancer care journey: Results from the first annual EGFR Resisters Patient and Caregiver Summit.
e13781 Background: Social isolation, loneliness, and lack of shared support networks are associated with increased psychos...
Oncological safety of oncoplastic breast conservation surgery: Experience of over a decade in early and locally advanced breast cancer from a tertiary care cancer center in India.
584 Background: Oncoplastic breast conservation surgery (O-BCS) is the norm. O-BCS improves cosmetic outcomes by restoring...
Blinded comparison of natural killer cell detection with AI-driven nanophotonic imaging versus traditional spectral flow cytometry: Development of the CB-Scout assay.
e14539 Background: Chimeric antigen receptor natural killer (CAR-NK) cells and in vivo CAR-T therapies are emerging as pro...
ZIP-code–level distress as a predictor for advanced stage and mortality in female breast cancer across a multiethnic cohort in Hawaiʻi.
1649 Background: Native Hawaiian and Pacific Islander (NHPI) patients experience worse breast cancer outcomes; however, th...
Recurrence patterns and survival in hormone receptor-positive/HER2-negative early breast cancer: A retrospective analysis from a public oncologic institution in Peru.
e23402 Background: Patients (pts) with hormone receptor (HR)-positive/HER2-negative early breast cancer (EBC) face a conti...
Feasibility and preliminary efficacy of a 12-week remotely delivered exercise program in patients receiving immunotherapy: A phase II randomized controlled trial.
1638 Background: Patients with advanced cancer receiving immunotherapy experience reduced physical function, increased sym...