Journal of Clinical Oncology
Articles in this Issue
De-escalate surgery of primary lesions after neoadjuvant immune-combination therapy in locally advanced oral squamous cell carcinoma: The 5-year survival results of two single-arm trials.
e18121 Background: Neoadjuvant immune-combination therapy (NAIT) followed by surgery and adjuvant therapy has been widely...
MAIN-CAV: Phase III randomized trial of maintenance cabozantinib and avelumab versus avelumab after first-line platinum-based chemotherapy (PBC) in patients (pts) with locally advanced/metastatic urothelial cancer (la/mUC; Alliance A032001).
4514 Background: Maintenance avelumab is a standard of care in patients (pts) with la/mUC who do not progress after first-...
Efficacy and safety of disitamab vedotin in patients with HER2-expressing locally advanced or metastatic urothelial carcinoma: A systematic review and meta-analysis.
e16577 Background: Urothelial carcinoma (UC) is the 4th among most commonly diagnosed malignancy, notorious for poor outco...
Sociodemographic variation in intracoronary imaging utilization among patients with active malignancy undergoing percutaneous coronary intervention: A National Inpatient Sample analysis.
e13697 Background: Intracoronary imaging–guided percutaneous coronary intervention (PCI) is associated with improved proce...
Bridging the gap: Nationwide genetic counsellor’s survey insights to plan a scalable framework for cancer genetic counselling in India.
e13550 Background: Genetic counselling (GC) is central to precision oncology, guiding appropriate genetic testing for trea...
Defining outcomes and risk of second primary malignancy (SPM) in patients with multiple myeloma (MM) in a large, integrated health system.
e19560 Background: Despite significant improvements in overall survival over the past 3 decades, MM is still an incurable...
Transcriptional correlates of <i>ARNT</i> expression and its impact on survival outcomes in clear-cell renal cell carcinoma (ccRCC).
e16554 Background: Encoded by ARNT , hypoxia-inducible factor-1β (HIF1β) is an obl...
Training fellows in genomic oncology: A pilot team-based workshop.
9024 Background: Genomic oncology (GO) is central to diagnosis and management of patients with cancer. However, GO trainin...
Early G-CSF after venetoclax-based induction for acute myeloid leukemia: Multicenter associations with infections, neutrophil recovery, and early mortality.
6518 Background: Venetoclax-based induction has improved remission rates in acute myeloid leukemia (AML) but is associated...
Hypercalcemia as a marker of in-hospital mortality and resource utilization in breast cancer: A national analysis.
e12711 Background: Hypercalcemia is a well-recognized oncologic emergency associated with advanced malignancy and poor out...
Laminectomy versus laminoplasty in the surgical management of long-segment intradural spinal tumors: Any difference in neurological outcomes?
e14069 Background: Laminectomy (LAMT) and laminoplasty (LAMP) have been widely applied on patients with spinal cord tumors...
Shifting etiologic burden of hepatocellular carcinoma hospitalizations in the United States, 2016–2022: A National Inpatient Sample analysis.
e16345 Background: The epidemiology of chronic liver disease is evolving with widespread use of direct-acting antivirals (...
Evaluation of xenograft alignment with patient tumors to inform treatment studies in uterine carcinosarcoma.
e17647 Background: Accurate representation of patient tumors is critical to study the factors affecting treatment response...
Knowledge of breast cancer warning signs and risk factors and their association with stage at diagnosis among women in Abuja, Nigeria.
e22538 Background: Late-stage presentation of breast cancer remains common in low- and middle-income countries and contrib...
Immune cell profiling by spectral cytometry to predict response to avelumab in advanced bladder cancer patients.
e14529 Background: Bladder urothelial cancer is a common neoplasm with a significant proportion of patients who progress t...
Comeback from long-course ADT with relugolix (rel) and darolutamide (daro) in hormone-sensitive prostate cancer (PC) (CLEARED).
5083 Background: The oral luteinizing hormone releasing hormone antagonist rel and androgen receptor pathway inhibitor (AR...
Transient prostate-specific antigen flare induced by lutetium Lu 177 vipivotide tetraxetan in patients with metastatic castration resistant prostate cancer.
5078 Background: Prostate-specific antigen (PSA) flare, an initial rise in PSA that subsequently falls, is a well-known ph...
Development of an endometrial cancer test from a vaginal swab.
5624 Background: Endometrial cancer (EC) is the most common gynecologic cancer and abnormal uterine bleeding (AUB) is the...
Long-term responders to trifluridine/tipiracil plus bevacizumab in previously treated metastatic colorectal cancer: Results from the BeTAS real-world study.
3583 Background: The phase III SUNLIGHT trial established trifluridine/tipiracil plus bevacizumab (FTD/TPI+BEV) as a stand...
Large-scale EMR-based machine learning for early risk stratification of colorectal cancer.
e15513 Background: Early detection of colorectal cancer (CRC) substantially improves outcomes; however, age- and symptom-b...
Real-world trends in the evolving use of first-line therapy in metastatic castration-sensitive prostate cancer patients (mCSPC) in the United States.
e23384 Background: Management strategies for frontline therapy of mCSPC is rapidly evolving. Current standards of care inc...
CIDER: Secure high-throughput extraction of clinical variables from non-English pathology reports with local large language models.
e13676 Background: Clinically relevant information is primarily embedded in unstructured narrative documents, limiting the...
Bevacizumab rechallenge in platinum-resistant ovarian cancer: Evidence from a propensity score–matched analysis.
5607 Background: Bevacizumab is approved for the treatment of ovarian carcinoma across multiple disease settings, from fir...
Soft tissue and bone/joint sarcoma disaggregation in minorities.
e23100 Background: Hispanic and APPI populations are usually aggregated in large databases when there can be a difference...
Mortality trends from sepsis and gastrointestinal cancer among United States adults: A CDC WONDER–based analysis.
e15673 Background: Sepsis is a major contributor to mortality among patients with gastrointestinal (GI) cancers. Populatio...