Browse Articles

Unified Organocatalytic Enantioselective Approach to Axially Chiral Spiranes and Alkylidenecycloalkanes

Synthesis and characterization of electrochemically polymerized indole on screen-printed Ag-conductive transparency sheet for enzymatic biofuel cell applications

Inverse Design of Anthraquinone-Mimicking COFs via Electronic Fingerprints for Sacrificial-Agent-Free Photocatalytic H ₂ O ₂ Production under Visible Light

Eyes closed single-leg stance test detects subtle sensorimotor decline in early multiple sclerosis

Site-Specific Raman Probes Reveal Droplet Aging and Residue-Level Fibril Polymorphism in TDP-43 _CTD

Evaluation of our new three-dimensional navigation system in robot-assisted partial nephrectomy

Dynamic Structural Self-Optimization in Mn and Ta Codoped RuO ₂ for Efficient and Long-Term Acidic Water Oxidation

Influence of cooling rates on the fracture properties of asphalt concrete subjected to freeze-thaw cycles

Correction to “An Amino-Acid-Derived Metal–Organic Framework with Large Pores for Unspecific Enantioseparation”

Effects of restricted compared to free arms motion during standing and walking at height in healthy adolescents

Abstract In adults, it is firmly established that height-induced postural threat as well as restriction of arms motion led to detrimental effects on emotional state and standing/walking outcomes. However, little is known about how both factors influence subjective and objective outcomes in adolescents where mechanisms to control standing and walking are still not adult-like. This work investigated emotional state and performance outcomes while standing and walking with free and restricted arms motion at ground level and at height. Twenty-five and 28 adolescents were recruited for study 1 (standing) and study 2 (walking), respectively. Participants stood (tandem stance) or walked (5 m at self-selected speed) with free or restricted arm position at both ground-level (no threat) and 80 cm above ground (threat). Postural sway (i.e., amplitude, frequency, sample entropy) and spatiotemporal gait (i.e., walking speed, time, steps, cadence) parameters were used as objective performance outcomes. Self-reported emotional state responses (i.e., balance confidence, fear of falling, perceived instability, conscious balance processing) were used as subjective indicators. In both studies, height-induced postural threat led to detrimental effects on emotional state and standing/walking outcomes. Further, adolescents in study 1 adopted a postural control strategy that differed from a “stiffening” response reported for young adults. In addition, threat-related deteriorations in spatiotemporal gait outcomes (study 2) were further amplified when arms were restricted. The findings replicate but also expand previous research about the effects of postural threat and restricted arms motion on emotional state and standing/walking outcomes and provide additional knowledge on how young people act under these conditions.

De Novo Design of Near-Infrared Fluorescence-Activating Proteins

Transcriptome analysis across reproductive stages in peripheral blood of female brown bears: a pilot study

Stable Diradical to Pentaradical Cobalt–Dithiolene Complexes: Toward Cobalt-Based Multinuclear–Multiradical Complexes

Gaze and gait dynamics are shaped by terrain type during urban walking

Abstract The structure of the environment fundamentally shapes how humans see and move. Walking through the city requires the continuous coordination of eyes, head, and body movements, revealing the active role of perception in guiding locomotion. Here, we used wearable eye-tracking, foot-mounted inertial sensors, and GPS to examine how terrain type modulates gaze behaviour and locomotor dynamics during naturalistic urban walking. Twenty young adults walked along routes comprising flat pavements, cobblestones, and dirt paths while their gaze, head orientation, and gait were recorded. Gaze behaviour varied systematically with surface irregularity: cobblestones and dirt paths elicited more frequent downward, proximal gaze and larger downward head-pitch deviations. Gait also adapted, with slower pace, shorter strides, and reduced cadence on uneven surfaces. Spatial correlations revealed tightly coupled adjustments between gaze and gait, indicating continuous sensorimotor coordination. These findings show how the physical structure of urban environments shapes predictive visuomotor strategies during real-world locomotion, providing a multimodal foundation for understanding embodied cognition in motion.

Phenoxazines with a Phototransferable <i>N</i> -Acetyl Group and Acrylate Linker: Assembly by C–H Activation, Photoconversion to Fluorescent Dyes, Biolabeling, and Super-Resolution Imaging

Association between recombinant human growth hormone therapy and refractive status in Korean children with idiopathic short stature: a cross-sectional study

Electronic Transport in Porous Nanocrystals Enables Ultrasensitive Consistent Detection of Sulfur Dioxide under Variable Humidity

Enhancement of antebrachiocarpal arthrodesis using a collagen–chitosan composite enriched with advanced platelet-rich fibrin in a rabbit model

Abstract Arthrodesis is a pivotal surgical intervention for achieving joint stability and alleviating pain in cases of severe joint destruction. However, attaining reliable bone fusion remains challenging, frequently requiring adjunctive biomaterials to optimize osteogenesis. The present study was designed to investigate the combined regenerative effect of a collagen–chitosan composite integrated with A-PRF on antebrachiocarpal joint arthrodesis in a rabbit model. This experimental study involved 16 clinically healthy male New Zealand White rabbits. All animals underwent surgical curettage of the antebrachiocarpal joint cartilage. The rabbits were randomly allocated into two groups: a Control group (C) and a treatment group (COL/Cs -A-PRF). Over the 12 weeks, the Col/Cs/A-PRF group demonstrated marked radiological improvement. Radial cortical thickness (RCT) increased from 0.91 ± 0.13 mm to 1.4 ± 0.05 mm ( p  &lt; 0.001). Radial bone mineral density (RBMD) progressively increased, reaching approximately 780 HU ( p  = 0.0007). Intra-articular tissue mineral density increased to around 370 HU. Joint space narrowing progressed from approximately 1.0 mm to 0.3 mm ( p  &lt; 0.0001), with the fusion ratio reaching nearly 70% ( p  &lt; 0.0001). Additionally, carpal bone density increased to approximately 990 HU ( p  &lt; 0.0001). The presented findings demonstrate that the collagen–chitosan composite augmented with A-PRF significantly improves bone regeneration and joint fusion in a rabbit model of antebrachiocarpal arthrodesis, highlighting its innovative and translational potential.

Dark Side of <i>Escherichia coli</i> Biogenic Inner Membrane: Overabundance of Three Main Phospholipids on Cytoplasmic Leaflet

In vivo assessment of anti-helminthic and anti-inflammatory effects of Fucoidan on Schistosoma mansoni immature stages

Abstract Schistosoma mansoni is a major cause of schistosomiasis, a neglected tropical disease that induces granulomatous inflammation, fibrosis, and liver damage. Fucoidan (FUC), a sulfated polysaccharide from brown seaweed, was evaluated for its anti-helminthic, anti-inflammatory, and antifibrotic effects against immature stages of  S. mansoni  in mice. Forty-eight CD-1 Swiss male albino mice were infected and allocated into six groups: infected untreated control, praziquantel-treated, and FUC-treated groups at 7, 21, 35, and 42 days post-infection. Treatment with FUC at 7, 21, and 35 dpi significantly reduced worm burden, granuloma size, fibrosis, and the expression of TNF-α, IL-1β, and iNOS in liver tissue. The strongest antipathological effects were observed with early-to-mid treatment, particularly FUC7, FUC21, and FUC35. In contrast, FUC42 showed weaker benefit, indicating that efficacy is timing-dependent. These findings suggest that FUC may be a promising candidate for early intervention in  S. mansoni  infection.