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From bench to bread: how science can enhance your hobbies
Spatiotemporal dynamics and influencing factors of land carbon stock in Chengdu Plain using an integrated model
Surface-Conducting Lithium Superionic Conductors for Solid-State Batteries
Unmanned aerial vehicle routing based on frog-leaping optimization algorithm
Cathelicidin-BF: A Potent Antimicrobial Peptide Leveraging Charge and Phospholipid Recruitment against Multidrug-Resistant Clinical Bacterial Isolates
YOLOv8 and point cloud fusion for enhanced road pothole detection and quantification
Dopamine fast determination in pharmaceutical products using disposable printed electrodes modified with bimetal oxides carbon nanotubes nanocomposite
Abstract Dopamine is an essential neurotransmitter involved in the regulation of our pleasure, motivation, and other biological functions. Thus, tracking and monitoring the biological dopamine level is crucial for the rapid and effective treatment as well as for the diagnosis of the neurodegenerative and neurological disorders. Nanostructured electrochemical systems are tested and validated as promising methods for dopamine detection. In this study, carbon nanotube-anchored bimetallic manganese/copper bi-oxides nanocomposite-modified screen-printed carbon electrodes (Mn/Cu oxides @CNTs-SPCEs) were exploited for the electrocatalytic oxidation and direct determination of dopamine. From the morphological analysis, the particle size of the bimetallic oxides spherical nanoparticles was ranged from 9.0 to 45 nm, while the electrocatalytic activity of nanocomposite towards dopamine oxidation was examined by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) to demonstrate the acquired high sensitivity and selectivity. The optimized DPV assay provided a wide linear dynamic range of dopamine concentrations (from 0.001 to 140 µM), and a low detection limit of 0.3 nM. Eventually, the newly modified electrochemical method was applied for dopamine detection in pharmaceutical products with high accuracy.
Daily briefing: Drug makes people’s blood poisonous to mosquitoes
Photoinduced, Copper-Catalyzed Enantioconvergent Synthesis of β-Aminoalcohol Derivatives
LSTM-JSO framework for privacy preserving adaptive intrusion detection in federated IoT networks
Fluorogenic, Subsingle-Turnover Monitoring of Enzymatic Reactions Involving NAD(P)H Provides a Generalized Platform for Directed Ultrahigh-Throughput Evolution of Biocatalysts in Microdroplets
Analysis of the relationship between rod cell membrane currents and the photoreceptor component of electroretinograms using a cable model
Reticular Design and Synthesis of Covalent Organic Frameworks with Irregular Hexagonal Tiling
Transcriptome analysis reveals the expression of genes involved in the formation of petal variegation in Impatiens morsei
Abstract Impatiens morsei is an annual or perennial flower that is a member of the Impatiens genus in the Balsaminaceae family, with pink flowers and dark purple spots on the vexil and wing petals, which is important for the study of new flower colors of Balsaminaceae. However, there has been no study on the flavonoid biosynthesis pathway and carotenoid biosynthesis pathway of I. morsei and the mechanism of its pigment formation is still unclear. Transcriptome sequencing of spotted and non-spotted regions was performed using the petals of I. morsei at full bloom as test material. The results showed that (1) After transcriptome sequencing, 39,917 unigene sequences and 39,110 differentially expressed genes were obtained, and the number of genes that are down-expressed was higher than genes that are up-expressed. (2) Three key genes in the flavonoid biosynthetic pathway, FLS, PAL, and CHS1, were screened out. Additionally, two key genes in the carotenoid biosynthetic pathway, ABA1 and CCS, were identified. Furthermore, two regulatory genes, MSI4 and CPC, were also selected.and analyzed the spatiotemporal expression patterns of these seven genes. The results of this study lay a theoretical foundation for the study of the formation mechanism of floral spots in I. morsei.