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Observation of *N<sub>2</sub>H<sub>3</sub> Intermediates by In Situ Electrochemical SERS: New Pathway of Ammonia Oxidation on High-Durability PtIr Catalysts
Eu isotope fractionation and hydrothermal alteration
Electron Donors in the Intertwined Interface Restore Oxy-Substituted Selenides
Ensemble-based sesame disease detection and classification using deep convolutional neural networks (CNN)
Heme-Like {CoNO}<sup>9</sup>, (STTP<sup>•–2</sup>){CoNO}<sup>9</sup>, and {CoNO}<sup>10</sup> Complexes Supported by 21-Thiaporphyrin Macrocycle
Depression mediates the association between lipid accumulation products and overactive bladder
Triptycene-Based 2.5-Dimensional Metal–Organic Frameworks: Atomically Accurate Structures and Anisotropic Physical Properties from Hydrogen-Bonding Bridged Protonated Building Units
Exploring associations between breast tumor inflammatory gene expression and mammographic calcifications and masses in a community-based population
Mechanical-Bond-Enabled Highly Efficient Charge Separation in a Light-Harvesting Hetero[2]Catenane
Correction: Risk assessment of Escherichia coli O157:H7 along the farm-to-fork fresh-cut romaine lettuce supply chain
Breaking a Lewis Acidity Trend for Rare Earths by Excited State Quenching
Invulnerability bias in perceptions of artificial intelligence’s future impact on employment
Topochemical Reaction Involving Double-to-Single Layer Conversion: Mo<sub>3</sub>Ta<sub>2</sub>O<sub>10</sub>N with a Kagomé Lattice
Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study
Entropy-Driven Structural Evolution in Ceramic Oxides
Development of a deep learning based approach for multi-material decomposition in spectral CT: a proof of principle in silico study
Abstract Conventional approaches to material decomposition in spectral CT face challenges related to precise algorithm calibration across imaged conditions and low signal quality caused by variable object size and reduced dose. In this proof-of-principle study, a deep learning approach to multi-material decomposition was developed to quantify iodine, gadolinium, and calcium in spectral CT. A dual-phase network architecture was trained using synthetic datasets containing computational models of cylindrical and virtual patient phantoms. Classification and quantification performance was evaluated across a range of patient size and dose parameters. The model was found to accurately classify (accuracy: cylinders – 98%, virtual patients – 97%) and quantify materials (mean absolute percentage difference: cylinders – 8–10%, virtual patients – 10–15%) in both datasets. Performance in virtual patient phantoms improved as the hybrid training dataset included a larger contingent of virtual patient phantoms (accuracy: 48% with 0 virtual patients to 97% with 8 virtual patients). For both datasets, the algorithm was able to maintain strong performance under challenging conditions of large patient size and reduced dose. This study shows the validity of a deep-learning based approach to multi-material decomposition trained with in-silico images that can overcome the limitations of conventional material decomposition approaches.